Introduction: Down syndrome is a genetic condition arising from three chromosomal abnormalities, namely trisomy 21 (the most well-known); translocation, and/or mosaicism. This chromosome change occurs in the formation of the fetus, in more detail at the time of cell division, which will characterize the signs and symptoms of the syndrome. Objective: The purpose of this article is to research the main scientific findings in the last 10                years regarding physical therapy treatments, to verify the best techniques and their respective results, and to address the role of physiotherapy in the development of children with Down syndrome. Methods: The research only included studies published in the period from 2009 to 2019, systematic review articles and limited the Portuguese and English languages ​​were excluded, excluding all incomplete articles, duplications, abstracts that did not address, and those works that do not have a scientific basis. Results: In this systematic review, it can be seen that the main research results were disseminated and stored in databases (SciELO, Medline, and LILACS), focusing on the study of and DS patients, specifical children in early childhood. There are few studies on down syndrome in adults. Another important aspect is the concentration of research in the field of sports physiotherapy, few studies have focused on other areas of physiotherapy, such as respiratory, cardiovascular, and cognitive physiotherapy, which go in the opposite direction. Conclusion: Physiotherapy for patients with DS can improve the quality and life expectancy of these individuals, but the needs of patients with this syndrome involve some physical, physiological and psychological aspects and require the attention of a multidisciplinary team.

Introduction: At the end of 2019, more specifically in December, the outbreak of the new coronavirus - Sars-Cov-2, which caused pneumonia, emerged in Wuhan, and soon spread throughout China, where researchers began to suspect a possible pandemic. , being a disease that causes a deficiency of structures of the respiratory system, leading to alterations in breathing functions, with respiratory muscle deficiencies and exercise tolerance. During the pandemic peak still in Wuhan, the main radiographic findings in hospitalized patients revealed bilateral opacity on computed tomography (CT) examination, lobular and subsegmental consolidation areas, ground-glass opacities, consolidation with rounded morphology, and peripheral pulmonary distribution. Aims: Analyze through the available literature review the main radiological alterations caused by Sars-Cov-2. Methodology: This is an integrative literature review using PubMed, Scielo, Google Scholar, Microsoft Academic databases. Inclusion criteria were complete and original articles in English and Portuguese. Duplicates and other literature reviews were excluded. Results: Radiographic findings are different in the early and advanced phases of the disease, but characteristic signs such as the matte glass pattern were found in both phases. Conclusion: The radiographic findings of patients diagnosed with COVID-19 are not the main criteria for clinical diagnosis, but knowledge of characteristic symptoms is fundamental. Therefore, the multidisciplinary team must discuss the radiological findings most common to the virus, this will directly aid early diagnosis, in addition to reducing the high mortality rates globally.

Epidemiological Analysis of Determinants in ICUMortality in the State of Tocantins in Brazil 1. Introduction "Everyone's right and the State's duty", is what the inscription of health in the Federal Constitution of 1988 provides, and must be "guaranteed by social and economic policies aimed at reducing the risk of disease and other aggravations" (BRASIL, 1988).). Until then, the Ministry of Health participated with less than 20% of the federal resources destined to the financing of health in the country, today, the resources destined to health, do not differ from countries that managed to obtain better assistance to the population than the one that today, in average, is provided to Brazilians, hovering around 8% of GDP. According to IBGE data, financing and investment in health in the country predominantly incurs in the private service, which provides assistance to only 20% of the population. Efficiency in health investments and the development of strategic planning has become essential in health policies, since just spending larger fractions of GDP does not mean better health conditions (COSTA et al. 2019).According to data from the CNES (national council of health establishments), the health system in Tocantins provides 176 general ICU (intensive care unit) beds, 86 of which are provided by the SUS (Unified Health System) and ninety by the private and supplementary system. with the largest number located in the capital Palmas (88 beds), followed by the municipality of Araguaína, with 65, and Gurupi, with 23. Between the years 2020 and 2021, 419 additional COVID-19 ICU beds were made available in reason for the pandemic.With regard to general ICU beds, the biggest determinants of the demand for beds in Tocantins due to morbidity are cardiovascular and respiratory diseases, followed by external causes related to multiple traumas (REIS, 2018). According to data provided by DATASUS (Information Department of the Unified Health System) there were about 61 thousand hospital admissions in the state related to cardiovascular diseases between 2016 and 2021, followed by 53 thousand admissions, in the same period, related to cardiovascular diseases. external causes. According to Simão et al. ( 2013) the main etiological factors of cardiovascular diseases are systemic arterial hypertension, dyslipidemia, diabetes

Fibromyalgia (FM) is a chronic and rheumatological disease that causes generalized pain by the body, being able to dispose of the person from any activity, even the simple act of sleeping, because of the pains become unbearable. Traditional Chinese Medicine (TCM), is one of the options for an indication of acupuncture used as an alternative for the treatment of fibromyalgia and the possibility of offering patient improvement in the quality of life. This research aims to corroborate through a bibliographic review of recent studies and evidence that designates the effectiveness of acupuncture for patients with fibromyalgia. The methods used for this review work were based on the methodology of the experimental factorial planning article: A brief review, published in the journal International Journal of Advanced Engineering Research and Science (IJAERS). Due to the studies done, it was explicit that the treatment for fibromyalgia using acupuncture has great benefits because patients suffering from pain and use this technique as a treatment option make less use of medication, have less frequent crises and, as a result, more quality of life. It is concluded that acupuncture has physiological bases that prove its effectiveness in the treatment of fibromyalgia symptoms, thus becoming another relevant treatment option for patients with FM to increase their quality of life.

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