This report highlights details on a pregnant case of COVID-19 who unfortunately did not survive. This 27-yearold woman at her 30 and 3/7 weeks' gestation was referred to our center with fever, myalgia, and cough. The laboratory investigations showed leukopenia and lymphopenia as well as increased creatinine and CRP levels. The first chest X-ray (faint bilateral patchy opacities) and CT scan (some faint subpleural ground-glass opacities associated with pleural thickening) were not typical for initial COVID-19 pulmonary infection, however, the treatment for COVID-19 was started. Due to respiratory distress, she was intubated and put under mechanical ventilation. After a while, the fetus was born with Apgar score of 0 and did not react to the neonatal cardiopulmonary resuscitation protocol. Finally, due to deterioration in the clinical and imaging findings, the patient was expired as a result of multi-organ failure. Following the death, autopsy was performed and the histopathologic evaluations of the lungs showed evidence of viral pneumonia (viral cytopathic effect and a mild increase in alveolar wall thickness) and ARDS (hyaline membrane). Also, reverse transcription-polymerase chain reaction (RT-PCR) confirmed SARS-CoV-2 infection in the lungs. To our knowledge, this is the first report of maternal death with confirmed COVID-19 infection.
Introduction: Diabetes is the most common endocrine disease, which affects about 150 million people worldwide. Disruption of the immune system and other factors reduces the resistance to microorganisms in diabetic patients. Therefore, the aim of this study was to determine the prevalence of Candida and its strains in diabetic and non-diabetic patients. Materials and methods: This cross-sectional and analytical study was conducted on 60 hospitalized patients, among whom 30 were diabetic and 30 were non-diabetic during June 2021 to December 2021. According to the location of the infection, sampling was done using a swab or a slow scalpel blade. Demographic information of patients such as: Age, gender, level of education, occupation, site of infection, underlying disease and drug use were collected. Results: The status of the frequency of isolated oral Candida showed no significant relationship between gender and the frequency of oral Candida (P=0.593). In our study there is no association between insulin intake, artificial teeth, smoking, antibiotic use, place of residence, level of education, age, duration of diabetes with Candidiasis (P>0.05). The results showed a significant relationship between the frequency of oral Candida isolated from diabetic and nondiabetic patients and the type of diabetes observed (P=0.008). Conclusion: In our research, there was a significant relationship between oral Candida infection and the type of diabetes and no significant relationship between diabetic and non-diabetic patients with the frequency of Candida and its strains.
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