Background:The main objective of this study was to demonstrate the effectiveness of daily measurements of liver enzymes along with c-reactive protein (CRP), and complete blood count (CBC) for the successful management of septic cases in neonates.Method: A sample of septic neonates (48 individuals), along with 40 non-septic neonates, was randomly selected for the daily measurement of liver function tests (aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP)), blood culture, CRP, and CBC during the routine medical treatments of sepsis cases in neonates. The abovementioned parameters were measured according to international laboratory standards. Data were statistically analyzed to determine whether there were correlations among parameters. Results:The data showed elevated levels of white blood cells (WBCs), ALT, AST, ALP, and CRP and a reduced level of platelets on the first day of medical treatment (on admission). Daily measurement of the parameters provides a trend with the direction of medical treatment. Strong correlations were found between CRP and blood parameters. Successful medical treatment indicated a continuous reduction of WBCs, ALT, ALP, AST and CRP and increased level of platelets to reach the values of the reference range and/or the control group at the end point. Conclusion:Daily measurements of ALT, AST, ALP and CRP along with blood counts are driving toward the successful diagnosis and management of septic cases in neonates. The implementation of these diagnostic parameters around the globe may reduce the morbidity and mortality in neonates.
Objective: To develop an optimal follow-up treatment for neonatal and nosocomial infections and to examine correlations between the C-reactive protein (C-RP) and platelets. Methods: A sample of 27 septic neonates and 14 non-septic neonates were selected for this study. The non-septic neonates served as a control group. Blood samples were collected from both groups and analyzed for bacterial contamination via blood culture, complete blood count (CBC), and C-RP, according to international laboratory standards. Blood collection and analysis were repeated every day during the follow-up treatments with antibiotics to evaluate the kinetics of C-RP. Results: Blood culture found E. coli and Staphylococcus aureus in the blood of the septic cases. Serum C-RP concentrations were at high levels (24 mg/dl) in the septic neonates and at normal levels (lower than 6 mg/dl) in the control group. Treatment with active antibiotics resulted in a drastic reduction of the C-RP values and helped to reach a normal level as in the control group. On the other hand, there were increases in the platelet levels as the C-RP levels decreased. This result indicates a strong negative association between C-RP and platelet levels in the septic group only. Statistical analysis shows significant differences between the mean C-RP serum concentrations of the sepsis and non-sepsis. Conclusion: blood culture, active antibiotics, and kinetic C-RP measurements during the medical follow-up treatment are strong driving parameters for the optimal and successful management of sepsis.
Introduction: Family planning importance is increasing progressively and is regarded as an essential part in every couple’s life. Family planning has a lot of benefits for the whole family as it provides a better control over the period between each pregnancy leading to a better balance over the personal, financial, and societal life. There are multiple birth control methods, from which couples can choose from with the assistance of their physicians since each method has its own advantages and disadvantages. Furthermore, some contraceptive methods may be more suited for a certain couple or situation than another one. This review of current methods aims to shed the lights on the various contraception options along with their advantages and disadvantages to aid providers in taking care of their patients. Methodology: A thorough search was carried out on PubMed using the most suitable keywords representing the aim of the present study. A total of 120 were found and based on whether they are suited to achieve the aim of the study, 28 were selected. Discussion: There is a great variety of birth control methods, and each has its associated advantages and disadvantages. Barrier contraceptive methods, most common of which are male condoms, are extremely popular in Western countries. Combined hormonal contraception methods which are available in the form of pills, patches, and rings. Progestin only contraception either in the form of a pill, injection or an implant is the most commonly used type among breastfeeding women. Furthermore, intrauterine devices are another effective contraceptive method which may be copper-based or hormonal-based. Conclusion: Contraception is an integral part of family planning, which can be achieved through a variety of methods. Each birth control method has its own pros and cons that should be explained to the couple clearly, so they can choose the method that is most suited for them.
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