Purpose: to evaluate Botox injection versus bilateral rectus muscle recession for treatment of basic exotropia. Methods: Of the 60 patients with basic exotropia included in a prospective com-parative clinical study which conducted at outpatient's clinic of ophthalmology, Menoufia University Hospital during March 2021 till June 2022 were eligible for inclusion. A detailed history of strabismus, complete ophthalmologic and orthoptic assessment were done. Results: there were no significant differences between the studied groups regarding angle of squint pre and post-operative (P=0.563, 0.145 respectively). Also, angle of squint was significantly improved after operation than preoperative among Botox injection group (3.72±1.96 vs 31.67±6.64, P<0.001), and patients with bilateral rectus muscle recession (2.89±1.32 vs 32.56±9.46, P<0.001). Conclusions: In the treatment of basic exotropia, Botox injection is as effective as bilateral lateral recession.
Purpose To study the relation between serum calprotectin level and acute noninfectious anterior uveitis in Egyptian patients. Methods An observational prospective study carried out at Menoufia University Hospital during the period from march 2021 till June 2022, after informed consent from all studied patients. This study included 20 eyes of patients with Acute Anterior Uveitis (AAU) and 20 eyes healthy individuals matched sex and age as the control group. Full history taking, ophthalmological examination and serum calprotectin levels were performed for both patients and controls. Results The majority of AAU patients' eyes (55%) had a moderate grade, followed by a faint grade (30%) and a pronounced grade (15%). Serum calprotectin levels were substantially higher in patients with acute anterior uveitis than in healthy eyes (61.45 ± 7.89 vs. 32.50 ± 11.64; 95% CI: 22.58–35.32; P < 0.001). In comparison to negative previous uveitis and mild to moderate anterior uveitis, serum calprotectin levels were substantially higher with positive previous uveitis (64.75 ± 4.65) and notable grade (67.00 ± 2.65). The serum calprotectin cutoff point for diagnosing AAU was 58.0, with sensitivity of 95% and specificity of 43%. Serum calprotectin had a cutoff value in the prognosis of AAU of 63.0, with a sensitivity of 91.7% and a specificity of 37.5%. Conclusion Serum calprotectin levels was significantly higher with positive previous uveitis and marked grade indicating a possible role of calprotectin in the pathogenesis of noninfectious AAU. Finally, we discovered serum calprotectin as a possible biomarker for predicting patients' mortality risk and the likelihood of developing anterior uveitis, whose prompt monitoring may enhance the prognosis of anterior uveitis.
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