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Purpose To investigate the correlation between changes in lamina cribrosa (LC) structure using enhanced depth imaging (EDI) and severity of visual field (VF) affection in primary open-angle glaucoma (POAG). Patients and Methods This prospective cross-sectional study was carried out on 52 glaucomatous eyes of 28 POAG patients who attended Tanta University Eye Hospital and 40 normal eyes of 20 age-matched normal subjects from April 2020 to March 2021. POAG patients were classified according to the modified Hodapp–Anderson–Parrish grading scale based on the MD of the standard automated perimetry (SAP) visual field into two groups: group (1) – mild-to-moderate POAG patients (MD ≤ 12 dB), group (2) – severe POAG patients (MD ≥ 12 dB) and the third group included normal (control) age- and gender-matched individuals. Results There was no statistically significant difference between the three groups regarding lamina cribrosa thickness nor lamina cribrosa area and there was no statistically significant correlation between MD and LC thickness, LC area (P-value=0.395 and 0.644). There was a statistically significant correlation between MD and anterior lamina cribrosa surface depth (P-value=0.002) and there was a statistically significant positive correlation between MD and prelaminar neural tissue (PLNT) thickness and prelaminar neural tissue (PLNT) area (P-value= 0.023 and <0.001, respectively). Conclusion EDI-OCT is a useful biomarker of structural changes in ONH and LC, and we recommended it to be a part of the routine monitoring of patients with POAG.

Background: Cataract extraction affects some of the anterior chamber (AC) parameters like AC depth (ACD) and the width of the AC angle. Different techniques are used to evaluate these effects before and after cataract extraction.

Purpose To determine the distribution and the anatomical characteristics of plateau iris (PI) in primary angle closure glaucoma (PACG) using ultrasound biomicroscopy (UBM). Methods Fifty UBM images of PACG cases were studied over one year by retrospective analysis. The data from UBM images including angle opening distance at 500 and 750 μm (AOD500 and AOD750), trabecular-iris angle (TIA), angle recess area at 750 μm (ARA750), maximum ciliary body thickness (CBTmax), anterior placement of ciliary processes (APCP), central anterior chamber depth (CACD), axial lens thickness (ALT), and ciliary sulcus status were analyzed and compared between the PI and non-PI cases. Results Eighteen cases had PI (36%). The mean AOD500, AOD750, and TIA were significantly smaller in PI than in non-PI eyes ( P = 0.01; P = 0.046; and P = 0.026). Values of the ARA750 and CBTmax were not significantly different between the two groups ( P = 0.208 and P = 0.368). CACD was deeper in the PI group ( P = 0.011). ALT was higher in the non-PI group ( P = 0.001). The mean APCP of the PI group was more than those of the non-PI group ( P < 0.001). The number of cases with obliterated ciliary sulcus in more than two quadrants was significantly more in the PI group ( P < 0.001). Conclusion Around one-third of PACG eyes were found to have PI on UBM imaging. The number of obliterated ciliary sulcus and APCP were important UBM parameters that help in PI diagnosis.

Purpose: To compare refractive outcome of posterior Optic Capture versus In-the-bag Implantation of Intraocular Lenses in Pediatric Cataract Surgery. Design: Prospective, randomized and comparative study. Methods: Forty eyes of 25 children (12 males and 13 females) were included in this study with unilateral or bilateral cataracts in the pediatric age during the period between October 2018 to July 2019. These children were diagnosed to have congenital or developmental cataracts. All children underwent cataract surgery and IOL implantation. In our study, all children were divided into two groups: group (A) included 22 eyes that underwent posterior capsulorhexis and anterior vitrectomy with IOL implantation entirely in the capsular bag and group (B) included 18 eyes that underwent posterior capsulorhexis and posterior optic capture of the IOL. Patient demographics, surgical intervention, presenting symptoms, postoperative refraction and follow up of refractive changes for 6 months were recorded. Results: Ten cases were unilateral and fifteen cases were bilateral. The mean age was 5.44 ±3.30 in group (A) while the mean age was 4.26±1.45 in group (B). At 1.5 month, the mean spherical error in group (A) was 2.85 ± 1.41 D  with range from 1 to 6.5D, and the mean spherical error in group (B) was 2.50 ± 1.70 D with range from -0.75 to 3.75 D with no statistically significant difference in both groups. The mean cylindrical error in group (A) was -0.96 ± 1.87 D with range from -3.5 to 2.25D and the mean cylindrical error in group (B) was -1.38 ± 1.79 D with range from -3 to 2D with no statistically significant difference in both groups. At 6 months, the mean spherical error in group (A) was 0.73 ±1.89 D  with range from -4.00 to 3.75D and the mean spherical error in group (B) was 0.00 ± 2.27 D with range from -3.50 to 2.7D with no statistically significant difference in both groups. The mean cylindrical error in group (A) was -1.21± 0.90 D with range from -2.75 to 1.25D and the mean cylindrical error in group (B) was -1.68 ±0.93 D with range from -3.00 to -0.75D with no statistically significant difference in both groups. Conclusion: There was no statistically significant difference between in-the-bag intraocular lens implantation and intraocular lens posterior optic capture in the term of post-operative refraction.  Posterior optic capture helped in preventing posterior capsule opacification (PCO) postoperatively in all cases.