This study suggests that hyperbaric oxygen treatment contributes to the healing of tracheal anastomosis following irradiation and may be a useful supportive treatment after tracheal resection and end-to-end anastomosis.

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Purpose: The standard treatment for locally advanced stage cervical cancer is definitive radiotherapy, the quality of which affects both survival and side effects. Brachytherapy is a major component of definitive radiotherapy; it is administered using different techniques and applicators. The purpose of this study was to dosimetrically compare tandem ovoid (T-ovoid) and tandem ring (T-ring) brachytherapy treatments. Material and methods: Both applicator sets were applied to the same 20 patients, and treatment plans were made three-dimensionally (3D), with high-risk clinical target volume (HR-CTV) and organs at risk contoured. The HR-CTV was defined according to post-external magnetic resonance results. The patients with residual tumors not exceeding one-third of the parametrium were included in this study, while patients with larger masses were excluded and received interstitial therapy. The doses were calculated for both plans. Optimization for the HR-CTV was made with the aim that the equivalent dose according to 2 Gy (EQD 2) of 90% of the HR-CTV (D 90) would be higher than 85 Gy, without exceeding the maximum dose for organs at risk. Then, pairwise dosimetric comparisons were performed. Results: Plans were compared dosimetrically according to the HR-CTV, point A and B doses, and organs at risk. Although the point A and B doses were higher with T-ovoid use, the 3D HR-CTV coverage was statistically better with T-ring application (EQD 2 of HR-CTV D 90 : 97.46 Gy for T-ring and 88.44 Gy for T-ovoid; p < 0.0001). In addition, the rectum and bladder doses were statistically lower with T-ring usage (EQD 2 of rectum, 2 cc; T-ring, 63.10 Gy; T-ovoid, 74.99 Gy; p < 0.0001; EQD 2 of bladder, 2 cc; T-ring, 85.26 Gy; T-ovoid, 89.05 Gy; p < 0.0001). Conclusions: In our study with a limited number of samples, T-ring applicator seems to offer better 3D brachytherapy dosimetry for both HR-CTV and nearby organs at risk.

Objective: The purpose of this study was to assess the sealing ability of three different temporary restorative materials on endodontic access cavities as compared to radiated and nonirradiated teeth. Materials and Methods: All teeth were randomly divided into two main groups according to the presence or absence of the radiotherapy. The specimens in these groups were then divided into three subgroups of 12 teeth each, and into two control groups of eight teeth each as negative and positive control groups. In radiotherapy groups, radiotherapy (1.8 Gy) was applied daily over 35 days resulting in a total application of 63 Gy. Standardized occlusal endodontic access cavities were prepared in all groups. A cotton pellet was placed on the pulp chamber. The access cavities were restored with three temporary filling materials; first fill, Cavit-G and Cavisol. The specimens were immersed in 2% methylene blue solution and centrifuged at 3000 rpm for 5 min. Results: Although there was no statistical difference among the three materials for the groups in which radiotherapy was not applied ( P > 0.05), it was found that the sealing abilities of Cavit-G and Cavisol were not affected by radiotherapy ( P > 0.05). However, the leakage values of the light-cured polymerized temporary filling material, first fill, were increased when radiotherapy was performed ( P < 0.05). Conclusion: The radiotherapy application reduces the sealing ability of the light-cured temporary filling material, first fill.