Th is paper presents the author's integrated regional studies during the last decade. Th e main purpose is to present an overall understanding of the geological structure, sedimentary basins and hydrocarbon systems of the whole Western Black Sea Zone (WBSZ). Th is study is based on original data from boreholes, seismic and gravity-magnetic surveys and hydrocarbon accumulations.Many geophysical borehole data obtained for WBSZ during the last 3-4 decades were interpreted mostly at a national level using diff erent approaches, terminology and nomenclature for the same or similar lithostratigraphic and tectonic units. Th erefore, a unifi ed approach to interpretation of borehole-seismic data and correlation of stratigraphic, sedimentological and tectonic units has a key importance for overall clarifi cation of the deep geological structure and the hydrocarbon challenges.A set of regional geological cross-sections along good quality basic seismic lines and basic boreholes was constructed. A detailed tectonic map of the WBSZ has been compiled by integrated interpretation of seismic borehole and gravitymagnetic data. Th e defi nition of hydrocarbon systems and promising exploration trends is made by source rock assessment, Oil-Oil and Oil-Source rock correlations, analyses of the reservoir/seal pairs and the hydrocarbon migration and accumulation. Genetic correlations are based on many Rock-Eval, Gas Chromatography/Mass Spectrometry (GC-MS) and carbon isotope analyses.Th e complex geological structure of the WBSZ is defi ned by four groups of tectonic units: (1) Western Black Sea basin (WBSB) -its western zone with the Kamchia and the Histria westward wedging branches (sub-basins); ( 2) portions of the Moesian, Scythian and East European platforms; (3) fragments of the North Dobrogea, Eastern Balkan, Eastern Srednogorie and Strandzha orogens; (4) Burgas and Babadag basins.Four diff erent oil genetic types have been identifi ed. Th ree main hydrocarbon systems with economic potential are defi ned, they relate to: WBSB and its Histria and Kamchia branches, the East-Varna trough and the Bourgas basin. Conceptual models for hydrocarbon systems and their prospect exploration trends are constructed.

Giriş Serebrovasküler hastalıklar nörolojik hastalıklar içerisinde, en sık görülen hastalık grubunu oluşturmaktadır (1). Özellikle gelişmiş ülkelerde ortalama insan ömrünün uzaması serebrovasküler hastalık görülme sıklığını arttırmıştır. İskemik inme etiyolojisinde sıklıkla büyük damarların aterosklerozu (BDA), arteriyel trombüs oluşumu, kardiyoemboli ve küçük damarlarda ateroskleroz yer alır (2). İskemik inmenin küçük bir kısmında ise kalıtsal hastalıklar, konjenital damar hastalıkları, santral sinir sisteminin primer ve sekonder vaskülitleri, serebral amiloid anjiopati, mitokondrial hastalıklar ve kan hastalıkları gibi etiyolojik faktörler saptanır. İnme alt tipini belirlemek için en çok kullanılan sınıflamalardan biri, TOAST (Trial of Org 10172 in Acute Stroke Treatment) sınıflamasıdır (3). Bu sınıflama başlıca etiyolojiye dayanıp, klinik özellikler ve yardımcı inceleme bulguları, hastanın hangi gruba sokulacağını belirler. Objective: We sought to determine whether each of mitral annular calcification (MAC), left ventricular hypertrophy (LVH) and aortic calcification (AC) contribute to the increased risk of acute ischemic stroke in patients with cryptogenic stroke. Material and Methods: Three hundred and thirty patients with acute ischemic stroke were evaluated with transthoracic echocardiography for MAC, LVH and AC. and these echocardiography findings were analyzed for any correlation with stroke etiology. Results: Three hundred and thirty patients with acute ischemic stroke were classified according to the etiology as cardioembolic (n=83), atherothrombotic (n=48), lacunar (n=49), cryptogenic (n=125), multiple etiological groups (n=25). Twenty (24.1%) patients with cardioembolic, 7 (14.6%) patients with atherotrombotic, 8 (16.3%) patients with lacunar, 20 (16%) patients with cryptogenic, 5 (8.3%) patients with multiple etiological factor had MAC (p>0.05). Sixty-four (77.1%) patients with cardioembolic, 41 (85.4%) patients with atherotrombotic, 41 (83.7%) patients with lacunar, 95 (76%) of patients with cryptogenic, 2 (8%) patients with multiple etiological factors had LVH (p>0.05). Forty-two (50.6%) patients with cardioembolic, 29 (60.4%) of patients with atherothrombotic, 31 (63.3%) of patients with lacunar, 76 (60.8%) patients with cryptogenic, 15 (10.6%) patients with multiple etiological factor had AC (p>0.05). Conclusion: This study shows that there is no association between the presence of mitral annular calcification, left ventricular hypertrophy and aortic calcification with cryptogenic stroke.