Meglumine has been found to be an efficient catalyst for the synthesis of structurally diverse tricyclic fused pyrazolopyranopyrimidines by one-pot, four-component reaction of ethyl acetoacetate, hydrazine hydrate, aromatic aldehydes and barbituric acid in water.

A bipyridine‐based covalent organic polymer (COP) was successfully synthesized by condensation of trimesoyl chloride (TMC) and 2,2′‐bipyridine‐5,5′‐diamine (Bpy) under ambient conditions. This material was modified by coordination of PdCl2 to COP framework, affording a hybrid material, Pd@TMC‐Bpy COP, which was applied as a highly efficient heterogeneous catalyst for Suzuki‐Miyaura reaction under ligand‐free conditions in ethyl lactate. The catalyst could be reused for five times without obvious loss of its activity.

The application of non-toxic and magnetically separable nano-CuFe 2 O 4 as an efficient catalyst for oxidative homo-and cross-coupling reaction of terminal alkynes is described. A wide range of symmetrical and unsymmetrical 1,3-diynes have been synthesized in moderate to good yields under ambient atmosphere. The nano CuFe 2 O 4 can be recovered with a magnet and reused at least five consecutive cycles with no appreciable loss of its catalytic activity.

: A simple, efficient and green protocol has been developed for the synthesis of polysubstituted dihydropyridines via one-pot, four-component reaction of aldehydes, arylamines, dialkyl acetylenedicarboxylate, and malononitrile. The reaction was proceeded at room temperature in the absence of catalyst in aqueous ethyl lactate under visible light irradiation. The main advantages of the present approach are mild reaction condition, high yield, no column chromatography, clean reaction profile, environmentally friendly and sustainable from the economic point of view

Meglumine Catalyzed Expeditious Four-Component Domino Protocol for Synthesis of Pyrazolopyranopyrimidines in AqueousMedium. -A facile and highly efficient protocol for the one-pot, four-component reaction of ethyl acetoacetate, hydrazine hydrate, aromatic aldehydes, and barbituric acid has been developed using meglumine as an inexpensive, biodegradable, and reusable catalyst. This methodology provides a mild and fast route to structurally diverse tricyclic fused pyrazolopyranopyrimidines in good to excellent yields. Simplicity, room temperature reaction conditions, a green solvent, an easy work-up process, inexpensive price, and reusability of the catalyst are the main advantages of this method. -(LI, X.-T.; ZHAO, A.-D.; MO, L.-P.; ZHANG*, Z.-H.; RSC Adv. 4 (2014) 93, 51580-51588, http://dx.doi.org/10.1039/C4RA08689A ; Coll. Chem. Mater. Sci., Hebei Norm. Univ., Shijiazhuang 050024, Peop. Rep. China; Eng.) -B. Guendogan 15-232