The world is experiencing pandemic of the COVID-19 now, a RNA virus that spread out from Wuhan, China. Two countries, China first and later Italy, have gone to full lock down due to rapid spread of this virus. Till to date, no epidemiological data on mental health problems due to outbreak of the COVID-19 and mass isolation were not available. To meet this need, the present study was undertaken to assess the mental health status of Chinese people. An online survey was conducted on a sample of 1074 Chinese people, majority of whom from Hubei province. Lack of adequate opportunities to conduct face to face interview, anxiety, depression, mental wellbeing and alcohol consumption behavior were assessed via self-reported measures. Results showed higher rate of anxiety, depression, hazardous and harmful alcohol use, and lower mental wellbeing than usual ratio. Results also revealed that young people aged 21-40 years are in more vulnerable position in terms of their mental health conditions and alcohol use. To address mental health crisis during this epidemic, it is high time to implement multi-faceted approach (i.e. forming multidisciplinary mental health team, providing psychiatric treatments and other mental health services, utilizing online counseling platforms, rehabilitation program, ensuring certain care for vulnerable groups, etc.). 19 cases found in China, where 64117 recovered and discharged from hospital where total death tolls reached 3177 (Worldometers, 2020, March 13). The COVID-19 is spread all across the world very rapidly (total affected cases 134769 and death 4983, Worldometers, 2020, March 13, 2020). The outbreak of COVID-19 spread over a very fast period, due to the Chinese Lunar New Year, which is the biggest temporary migration of the earth (Belluz, 2020). During this occasion under normal circumstances, around 3 billion domestic trips are made where 15 million are made only from the epicenter of COVID-19 Wuhan. In contemplation of curbing the outbreak, the Chinese government imposed the lockdown and restricted transportation. Chinese nationals confined themselves for an indefinite period as the part of the first level measure to major hazards public health emergency.