Low-flow capnography with Microstream technology accurately measured alveolar CO(2) in newborns without pulmonary disease, as demonstrated by normal PetCO(2)-PaCO(2) gradients. The measured PetCO(2)-PaCO(2) gradient, as expected, was significantly higher in newborns with pulmonary disease. We also identified four quantitative waveform parameters that may be useful in differentiating between mechanically ventilated newborn patients with and without lung disease.

Implementation of the I-PASS Nursing Handoff Bundle was associated with widespread improvements in the verbal handoff process without a negative impact on nursing workflow. Implementation of I-PASS for nurses may therefore have the potential to significantly reduce medical errors and improve patient safety.

Implementation of I-PASS has been associated with substantial improvements in patient safety and can be applied to a variety of disciplines and types of patient handoffs. Widespread implementation of I-PASS has the potential to substantially improve patient safety in the United States and beyond.