Mucormycosis is an opportunistic fungal infection indicating a high mortality rate. Among six varieties of involved sites, rhino cerebral mucormycosis (RCM) is not the most uncommon. During the COVID-19 pandemic, with the increase, in predisposing conditions incidence rate of mucormycosis progressed. For aggressive treatment, an early diagnosis can be armored to reduce morbidity and mortality. Clinically RCM poses non-specific symptoms and signs delaying diagnosis. This is associated with orbital cellulitis and sinusitis, one-sided headache behind the eye, diplopia, blurring of visions, nasal congestion, rhinorrhea, epistaxis, nasal hypoesthesia, facial pain and numbness, and a history of black nasal discharge. Not commonly the complications of cranial nerve involvement have been reported. In the present case series, three presentations of facial nerve palsy in COVID-19 associated with mucormycosis are added to the literature database.

Central giant cell granuloma (CGCG) is an uncommon, intraosseous, osteolytic, bony lesion of the jaw which is predominantly seen under the age of 30 years with female predominance and is common in the mandibular anterior region. The clinical behavior of the CGCG ranges from slow-growing asymptomatic to large-growing symptomatic osteolytic lesions. The etiology of CGCG is debatable, although, local trauma, inflammation, and hemorrhage have been suggested. Here is a presentation of a case report showing aggressiveness of CGCG with rapid growth involving the anterior region of the mandible associated with paresthesia, pain, mobility, cortical perforation, and showing a completely osteolytic nature. It was diagnosed by histopathological examination and immunohistochemistry. This case was treated surgically with no recurrence seen after a one-year follow-up with a good prognosis. Expansile and osteolytic bony lesions in the jaws or any radiolucency more than 2 cm CGCG should take into consideration as a differential diagnosis. Key words: Aggressive and non-aggressive lesions, Central giant cell granuloma, Diagnostic dilemma, follow-up, Recurrence

Aims: Report a rare case of Diffuse large B cell lymphoma (DLBCL) of the maxilla which is difficult to diagnose clinically and radiographically with a wide array of differential diagnosis lists. Presentation of Case: A case of a 16-year male with well-defined swelling in the posterior region of the right maxilla associated with pain, paraesthesia, and abnormal mobility of teeth which mimicked a localized periodontal abscess. The clinical diagnosis of DLBCL poses a challenge opening a wide array of false diagnostic impressions. Discussion: Traditionally lymphoma is classified into Hodgkin’s (HL) and non-Hodgkin’s lymphoma (NHL) and NHL involves the extra-nodal site including the gastrointestinal tract, central nervous system, skin as well as in the head and neck area involving waldeyer’s ring, buccal mucosa, tongue, maxilla, and mandible Conclusion: The diagnosis of DLBCL may get delayed with a wide range of differentials in the jaw. A false diagnosis like periapical pathology or other benign lesions would delay the treatment plan. Clinically any lesion suspicious of malignancy in the jaw requires the attention of clinicopathological and radiographic correlation with special diagnostic techniques like immunohistochemistry.

Central giant cell granuloma (CGCG) is an uncommon, benign, intraosseous bony lesion of the mandible and maxilla which is variably aggressive in nature. The incidence of an aggressive and recurrence nature is greatest in a female with a ratio of 2:1. Based on the clinical and radiographic features, Central giant cell granuloma can be classified as aggressive and non-aggressive lesions. Here we report a case of central giant cell granuloma in the posterior mandibular molar region which was aggressive in nature. The clinically and radiographically swelling was evaluated with displaced tooth, pain, cortical expansion, and root resorption. The treatment varies according to the nature of the lesion, this case was treated by conservative excision with continuity of the mandible. Key words: Aggressive, central giant cell granuloma, osteolytic lesion.

Odontogenic myxoma is a benign locally aggressive odontogenic tumor that arises from the mesenchymal portion of the tooth germ. They occur most frequently in the second or third decade of life and rarely occur before the age of 10 and after the age of 50. These are slow-growing tumors, but they may be locally aggressive, especially in the maxilla. Here we report the case of odontogenic myxoma in a 25-year-old male patient in the mandibular anterior region, which is usually seen in the posterior aspect of the mandible.