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Undifferentiated callus cultures of Costus speciosus yielded diosgenin, tigogenin, lanosterol and stigmasterol.-Very recently,

Oral telangiectatic granuloma is a benign hyperplastic lesion occurring in response to trauma or chronic irritation in the oral cavity. The characteristic histological appearance comprises of typical granulation tissue with a proliferation of small thin-walled blood vessels in the loose connective tissue. We describe a case of a 36-year-old female who had a swelling in the left maxillary region which was associated with the intrabony defect. An internal bevel gingivectomy was performed, and the histopathological report was suggestive of telangiectatic granuloma. The intrabony defect was managed with the placement of platelet rich fibrin plug in the defect. A follow-up at 6 months showed no recurrence and no loss in the width of keratinized tissue. The aim of this case is to highlight the rare association of intrabony defect with telangiectatic granuloma and the need for histopathological diagnosis in such lesions.

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Diosgenin has been reported earlier from tissue cultures of Costus speciosus.1'2) Furthermore, the enhancement of diosgenin has been obtained by feeding cholesterol to the undifferentiated suspension cultures of C. speciosus.^The application of various auxins and cytokinins for inducing organogenetic differentiation in tissue cultures has been extensively studied but very little is known of their influence on biochemical differentiation and the production of secondary metabolites by in vitro cultures of tissues and organs.4~8) There is no previous report on the latter aspect for C. speciosus, which is dealt with in the present communication.