Present article provides the results of a primary phytochemical analysis of Fritillaria karelinii (Fisch. ex D. Don) Baker (syn. Rhinopetalum karelinii Fisch. ex D. Don) from family Liliaceae Juss., collected from different fields of populations in the Almaty region. A comparative analysis of water-alcohol isolations allowed identifying three substances belonging to phenolic nature, and the quantitative contents of flavonoids (in the range of 0.7–1.03 % in terms of air dry matter) and some other biological active compounds (alkaloids, amino acids, organic acids). There is a correlation in the quantitative content of arginine (max) and methionine (min) out of 13 amino acids that were identified in bulbs of three studied samples. By accumulation of amino acids, the Ili plant sample shows quantitatively different from the other two, for example arginine, proline (0.475), leucine (0.372), lysine, valine, phenyl, threonine, and alanine (0.51–0.31) prevail, and methionine and histidine were less than 0.1 %. Valine, threonine and proline are contained in the range of 0.298– 0.193 %, while lysine, leucine, phenylalanine, and serine are in the range of 0.175–0.161 % for a sample collected near Nurly village. The content of other identified amino acids was below 0.15 %.

The article provides an analytical review of the current state of study of the Karelin grouse Fritillaria karelinii (Fisch. ex D. Don) Baker from the family. Liliaceae on literature, herbarium and field research materials undertaken in March 2020 on the territory of Almaty region on the basis of which described natural population and the peculiarities of distribution in the South-East of Kazakhstan the studied species, the bulbs of which in recent years have become the object of a natural and predatory harvesting on the territory of Almaty region with the aim of exporting raw materials to China, where they are applied in Chinese medicine to receive antitussives and expectorants. According to the literature, a number of species of Ryabchik was able to detect antihypertensive, antinociceptive (analgesic), anti-inflammatory, sedative and antitumor effects due to the presence of steroid alkaloids. Analysis of the collections of the herbarium Fund of the Institute of botany and phyto-introduction indicates a wide distribution of the studied species on the territory of Kazakhstan, about half of the samples of which are collected in the South-East of Kazakhstan. Phytocenotic and morphometric characteristics are given, as well as a map of the location of F. karelinii coenopopulations identified on the territory of the Almaty region. Comparative analysis of morphometric parameters of the Karelin river from three populations indicates that the ili population of the studied species is characterized by favorable environmental conditions and the absence of limiting factors. At the same time, the Kapshagai and Bogetinsky populations are subject to a strong anthropogenic load and need to be protected.

The article shows results of anatomical and morphological studies of the vegetative organs of Fritillariakarelinii from various populations of southeastern Kazakhstan, in which differences were found in the rate of developmentof aerenchyma, a number of vascular bundles in leaves and stems. It has been established that moisture conditions of thehabitats of the species affect a number of layers and the ordering of parenchymal cells in the structure of the root and stem,as well as development of the cuticle on the leaf surface. The revealed anatomical and morphological features of the speciescan serve as diagnostic signs of plant materials.