Metacognition and literacy skills are important in the 2013 curriculum because both things belong to 21st century expertises. The purpose of this study is to determine the metacognition and scientific literacy skills of the students in SMK Andalusia 1 Wonosobo in the 2018/2019 teaching year. This study uses a quantitative method with a descriptive approach. The results of the research show that students' metacognition abilities are still relatively low, especially in monitoring and evaluation indicators. Meanwhile, the scientific literacy skills shows that the average achievement reaches up to 89% in knowledge aspect. The results of these studies indicate that the results between metacognition skills are different from the scientific literacy ones. These results can also be used as a reference for developing better competencies by improving or creating innovations in the classroom learnings.