Introduction:One of the positive effects of brain stimulation is interhemispheric modulation as shown in some scientific studies. This study examined if a type of noninvasive stimulation using binaural beats with led-lights and sound would show different modulatory effects upon Alfa and SMR brain waves of elderlies and children with some disease types.Subjects: The sample included 75 individuals of both genders, being, randomly, divided in 6 groups. Groups were named elderly without dementia diagnosis (EWD), n=15, 76±8 years, elderly diagnosed with Parkinson’s disease (EDP), n=15, 72±7 years, elderly diagnosed with Alzheimer’s disease (EDA), n=15, 81±6 years. The other groups were named children with Autism (CA), n=10, 11±4 years, children with Intellectual Impairment (CII), n=10, 12 ±5 years and children with normal cognitive development (CND), n=10, 11±4 years.Instruments and procedure: Instruments were the Mini Mental State Examination Test (MMSE), EEG-Neurocomputer instrument for brain waves registration, brain stimulator, Digit Span Test and a Protocol for working memory training. Data collection followed a pre and post-conjugated stimulation version. Results: The results of the inferential statistics showed that the stimulation protocol had different effects on Alpha and SMR brain waves of the patients. Also, indicated gains in memory functions, for both, children and elderlies as related to gains in brain waves modulation.Conclusion: The results may receive and provide support to a range of studies examining brain modulation and synaptic plasticity. Also, it was emphasized in the results discussion that there was the possibility of the technique serving as an accessory instrument to alternative brain therapies.

ARTICLE Brain stimulation used as biofeedback in neuronal activation of the temporal lobe area in autistic childrenEstimulação cerebral usada como biofeedback na ativação neural do lobo temporal em crianças autistas Thus, it is generally accepted that individuals with some form of ASD display at least some impairment in recognizing emotions through facial expressions 4 , although there are a host of inconsistent results 5 . However, the automatic mirroring of affective gestures and expressions is also considerably weaker in infants with ASD 6 and the differences in emotion processing between typically developing individuals and their peers with ASD are also observable at a neural level 6 . ABSTRACTThis study focused upon the functional capacity of mirror neurons in autistic children. 30 individuals, 10 carriers of the autistic syndrome (GCA), 10 with intellectual impairments (GDI), and 10 non-autistics (GCN) had registered eletroencephalogram from the brain area theoretically related to mirror neurons. Data collection procedure occurred prior to brain stimulation and after the stimulation session. During the second session, participants had to alternately process figures evoking neutral, happy, and/or sorrowful feelings. Results proved that, for all groups, the stimulation process in fact produced additional activation in the neural area under study. The level of activation was related to the format of emotional stimuli and the likelihood of boosting such stimuli. Since the increase of activation occurred in a model similar to the one observed for the control group, we may suggest that the difficulty people with autism have at expressing emotions is not due to nonexistence of mirror neurons.Keywords: autistic disorder; mirror neurons; emotions. RESUMOO estudo verificou a capacidade funcional dos neurônios-espelho em crianças autistas. 30 indivíduos, sendo 10 portadores da síndrome autista (GCA), 10 com deficiência intelectual (GDI), e 10 não-autistas (GCN) tiveram registrado o eletroencefalograma da área do cérebro relacionada teoricamente com os neurônios espelho. O procedimento de coleta de dados ocorreu antes e após uma sessão de estimulação cerebral. Durante a segunda coleta de dados, os participantes tiveram de processar alternadamente figuras evocando sentimentos neutros, felizes e tristes. Os resultados provaram que, para todos os grupos, o processo de estimulação de fato produziu ativação adicional na área neural em estudo. O nível de ativação foi relacionada com o formato dos estímulos emocionais. Uma vez que o aumento da ativação ocorreu em um modelo semelhante ao observado para o grupo controle, pode-se sugerir que as pessoas com autismo têm dificuldade em expressar emoções não devido à inexistência de neurônios-espelho.Palavras-chave: transtorno autístico; neurônios-espelho; emoções.

Background: Motor Imagery (MI) represents the cognitive component of the movement and recruits dopaminergic systems. Objective: To investigate the role of dopaminergic system through the action of methylphenidate and risperidone over beta coherence during execution, action observation and motor imagery. Methods: Electroencephalography (EEG) data were recorded before and after the substance intake. For statistical analysis, a three-way ANOVA was used to identify changes in beta coherence induced by the group, task and the moment variables. Statistical significance was set at p≤0.007. Results: We found a main effect for group for C3/CZ, and a main effect for task for CZ/C4 pairs of electrodes. Furthermore, significant differences were found in the post-drug administration between groups for C3/CZ pair of electrodes, and between task for C4/CZ pair of electrodes. Conclusion: The administration of methylphenidate and risperidone was able to produce electrocortical changes of the cortical central regions, even when featuring antagonistic effects on the dopaminergic pathways. Moreover, the execution task allowed beta-band modulation increase. RESUMOIntrodução: A imagética motora (IM) representa o componente cognitivo do movimento e recruta os sistemas dopaminérgicos. Objetivo: Investigar o papel do sistema dopaminérgico por meio da ação do metilfenidato e da risperidona sobre a coerência em beta durante a execução, observação de ação e imagética motora. Métodos: Os dados de eletroencefalografia (EEG) foram registrados antes e depois da ingestão das substâncias. Para a análise estatística, uma ANOVA de três vias foi utilizada para identificar mudanças na coerência beta induzidas pelas variáveis grupo, tarefa e momento. A significância estatística foi estabelecida em p≤0,007. Resultados: Encontramos um efeito principal para o grupo C3/CZ e um efeito principal para a tarefa nos pares de eletrodos CZ/C4. Além disso, diferenças significativas foram encontradas após a administração da droga entre os grupos para o par de eletrodos C3/CZ e entre tarefa para o par de eletrodos C4/CZ. Conclusão: A administração de metilfenidato e risperidona foi capaz de produzir alterações eletrocorticais das regiões somatomotoras, mesmo apresentando efeitos antagônicos nas vias dopaminérgicas. Além disso, a tarefa de execução provocou maior modulação da banda beta. /0000-0001-5970-3497; Guaraci Ken TANAKA https://orcid.org/0000-0001-5222-0513; Juliana BITTENCOURT https://orcid.org/0000-0003-1959-6345; Mariana GONGORA https://orcid.org/0000-0001-9382-9958; Silmar TEIXEIRA https://orcid.org/0000-0002-9240-1228; Mauricio CAGY https://orcid.org/0000-0002-6488-842X; Henning BUDDE https://orcid.org/0000-0003-3526-0569; Marco ORSINI https://orcid.org/0000-0002-8948-3955; Pedro RIBEIRO https://orcid.org/0000-0001-8270-3663; Bruna VELASQUES https://orcid.org/0000-0001-9363-8932 Correspondence: Danielle Aprigio; Av. Venceslau Brás, 71/Fundos -Botafogo; 22290-

Aim: The present study investigated the differences between the Panic Disorder (PD) patients groups’ and healthy controls for the EEG alpha dynamics under the frontal cortex and reaction time during the oddball task. Material and Methods: The reaction time during the oddball paradigm concomitant to EEG alpha power was tested in nine PD patients and ten healthy controls before and after a computer simulation presentation. Results: The findings revealed a decrease in EEG alpha power in PD patients concerning the control group (p ≤ 0.0125). However, both groups demonstrated an increased cortical oscillation after the computer simulation, except for the Fp1 electrode during M3 moment in the experimental group. The experimental group has a fast reaction time compared to healthy individuals during the oddball task (p = 0.002). Conclusions: We propose that the decrease in EEG alpha power in the PD patients may indicate an increase in processing related to an anxiogenic stimulus and interference of the anxiety state that compromises the inhibitory control. The reaction time task reveals cognitive symptoms in the experimental group, which may be related to the faster reactivity and high impulsivity to stimuli.

São raros estudos que tratam da acurácia de parâmetros de trocas gasosas durante o esforço, com a população brasileira. OBJETIVO: Determinar a confiabilidade do consumo máximo de oxigênio (VO2max) e do limiar anaeróbio (LAn), assim como, a objetividade do segundo (LAn) em adultos jovens saudáveis. MÉTODOS: Foram aplicados dois testes de esforço máximo, a partir dos quais dois observadores independentes determinaram o LAn através do método de inspeção visual. Os dados foram tratados por meio da análise de regressão, coeficiente de correlação intraclasse (CCI), ANOVA com dois fatores com teste post hoc de Tukey e teste t pareado para alfa < 0,05. As variações intra-observadores e intra-sujeitos foram determinadas por meio do erro típico (s) e coeficiente de variação (CV). RESULTADOS: Não houve diferença significativa entre os testes para o VO2max e LAn. Não foram observadas diferenças significativas entre testadores para a determinação do LAn. O VO2max apresentou entre os dois testes CCI = 0,97, s = ± 0,14L • min-1 e CV = ± 5,5% e para o LAn o CCI = 0,90, s = ± 0,14L • min¹, e CV = ± 9,2%. A determinação do LAn interobservadores apresentou CCI = 0,95, s = ± 0,10L • min-1 e CV = ± 5,6%. CONCLUSÃO: O VO2max e o LAn foram medidas satisfatoriamente precisas.