A practical, large-scale process for the preparation of tetrahydro-l-methyl-3,3-diphenyl-Iff,3if-pyrrolo-[1,2-c] [1,3,2]oxazaborole-borane is reported. The title compound is a stable, free-flowing crystalline solid useful either stoichiometrically or catalytically for the enantioselective reduction of prochiral ketones. When used stoichiometrically to reduce acetophenone the enantioselectivity is >99.8% ee.
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