Aqueous extract of Phyllanthus niruri (200 mg/kg and 400 mg/kg. p.o. single dose) was tested for its diuretic activity and compared with the standard drug hydrochlorothiazide (10 mg/ kg p.o.; single dose). Significant increase in the volume of urine and excretion of sodium, potassium and chloride was recorded when aqueous extract of Phyllanthus niruri was administered to hydrated albino rats

Introduction: Diuresis is an important pharmacological property which is useful in many clinical conditions. There is a need of better diuretics with lesser adverse effects in comparison to currently available diuretics. The study aimed to evaluate the diuretic activity of aqueous extract of fruit pulp of Tamarindus indica L. in rats.Methods: The study was undertaken with aqueous extract of fruit pulp of Tamarindus indica in three doses: 300 mg/kg, 600 mg/kg and1200 mg/kg for its diuretic activity in comparison with standard (furosemide) and vehicle control (normal saline) in Wistar rats. Urine volume and electrolytes were measured after 24 hours of drug administration.Results: Aqueous extract of fruit pulp of Tamarindus indica at the dose of 1200 mg/kg exhibited significant diuretic activity (p<0.05) without significant natriuretic effect. Magnesium excretion was also significantly increased in comparison to control group.Conclusion: Aqueous extract of fruit pulp of Tamarindus indica has significant diuretic activity in Wistar rats.

Asparagus racemosus is a well known plant of medicinal value, with proved antioxidant, anti-inflammatory and immunomodulatory properties. Antioxidants are reported to enhance wound healing. The present study is aimed to investigate the wound healing profile of Asparagus racemosus on incision and excision wound models in rats. The aqueous extract of the roots of Asparagus racemosus is made use of to study the effect on wound healing in albino rats using incision and excision wound models in 200mg/kg and 400mg/kg orally for 10 to22 days. The skin breaking strength, epithelialisation period, wound contraction rate were estimated. The extract showed significant improvement in the epithelialisation period, remarkable enhancement of wound contraction rate, increased skin breaking strength in the test groups suggesting the possible utility of this plant to enhance wound healing.