A one-step process for the production of nanoparticles presenting advanced magnetic properties can be achieved using vapor condensation. In this paper, we report on the fabrication of Fe particles covered by a uniform MgO epitaxial shell. MgO has a lower surface energy than Fe, which results in a core-shell crystal formation. The particles are proven to be useful as as contrast agents for magnetic resonance diagnosis and heating mediators for cancer therapy through hyperthermia. They also have potential to be used in drug delivery and magnetic-activated cell sorting.Dear Editor, Enclosed is the paper "Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia" by Carlos Martínez-Boubeta et al. for your consideration as a potential contribution in the NanoMedicine. The manuscript, or any part of it, is not and will not be submitted elsewhere for publication while under consideration by Nanomedicine. All authors have seen and approved the submission of this manuscript.While a huge number of methods have been developed for the scalable synthesis and preparation of inorganic metal and semiconductor nanoparticles, only a few specialized techniques were reported for the preparation of coreshell nanoparticles. In this paper, we reported a novel and versatile technique for the preparation of injectable nanoparticle dispersions suitable to act as contrast agents for magnetic resonance imaging. Our ferromagnetic particles * Cover LetterWe wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.The manuscript has been read and approved by all named authors and that there are no other persons who satisfied the criteria for authorship but are not listed. We further confirm that the order of authors listed in the manuscript has been approved by all of us.We confirm that we have given due consideration to the protection of intellectual property associated with this work and that there are no impediments to publication, including the timing of publication, with respect to intellectual property. In so doing we confirm that we have followed the regulations of our institutions concerning intellectual property.We further confirm that any aspect of the work covered in this manuscript that has involved either experimental animals or human patients has been conducted with the ethical approval of all relevant bodies and that such approvals are acknowledged within the manuscript.Signed by all authors as follows:[LIST AUTHORS, and SIGNATURES dated on June 20 th , except otherwise stated]We suggest the following as the possible reviewers of this work: Jian-Ping Wang

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Magnetoresistive ceramics, based on half-metallic ferromagnetic oxides have received renewed attention in the last few years because of their possible applications. Here, we review some recent progress on the development of magnetoresistive ceramic materials such as La 2/3 Sr 1/ 3 MnO 3 and Sr 2 FeMoO 6 ceramic materials. We shall revisit their basic properties, the strategies that have been employed to understand and to improve their intrinsic properties, pushing the limits of their operation at temperatures well above room-temperature, and the development of some applications. This effort has required the contribution of a number of actors. Starting from research laboratories, it has progressively involved industries that nowadays are able to supply high quality raw-materials or to manufacture magnetoresistive components at large scale. Keywords: magnetoresistive ceramics, manganese oxides, magnetic sensorsCerámicas magnetorresistivas. Progresos recientes: desde el entendimiento básico a las aplicaciones.Las cerámicas magnetorresistivas, basadas en óxidos semi-metálicos ferromagnéticos han recibido una renovada atención en los últimos años debido a sus posibles aplicaciones. Se revisan aquí algunos de los recientes progresos en el desarrollo de materiales cerámicos magnetorresistivos como La 2/3 Sr 1/3 MnO 3 y Sr 2 FeMoO 6 . Se revisitan sus propiedades básicas, las estrategias empleadas para entender y mejorar sus propiedades intrínsecas, llevando sus límites de operación a temperaturas muy por encima de temperatura ambiente, y el desarrollo de algunas aplicaciones. Este esfuerzo ha requerido al contribución de un gran número de actores. Comenzando por laboratorios de investigación, se ha implicado progresivamente a industrias que hoy en día están capacitadas para suministrar materias primas de alta calidad o para fabricar componentes magnetorresistivos a gran escala. Palabras clave: cerámicas magneto-resistivas, óxidos de manganeso, sensores magnéticos