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iii this situation until further . S U~M . W M I " J~. KetzzyliFenicilli ti, 2 ,h-tlimt:thoxyphenylpenicillin, and 6-acninopenicillanic acid were compared with respect to several biochemical activities. 2,6-Dimethoxyphenylpenicillin and 6-minopenicillanic acid were hydrolyzed at very low rates, compared to the rate for benzylpenicillin, by partially purified concentrated cell-free preparations o€ penicillinase derived from B .ceyeus, and at still lower rates by analogous preparations from S. aureus. For S. aureus, but not B. cereus, the growth-inhibitory con-

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