There is still controversy regarding the value of arthroscopic suture of triangular fibrocartilage complex (TFCC) peripheral tears compared with open transosseous repair because only the latter method restores foveal insertions of TFCC in case of distal radioulnar joint (DRUJ) instability. Five classes of TFCC peripheral tears are recognized in a treatment-oriented algorithm based on arthroscopic findings, and indications to proper treatment are set accordingly. Complete repairable tears (class 2) and proximal repairable tears (class 3) are associated with DRUJ instability and require foveal reattachment of the TFCC. We describe a new arthroscopic technique to repair the foveal attachment of the TFCC with the use of a suture anchor, which is indicated for class 2 and 3 TFCC peripheral tears, instead of an open repair. This technique requires a dedicated working portal to approach the fovea ulnaris. This Direct Foveal portal is used to prepare the ligament and bone and to drill and insert a suture anchor loaded with a pair of sutures. Under arthroscopic vision, a suture is passed through each limb of the ligament and tied using a small knot-pusher. This arthroscopic technique restores original TFCC anatomy and adequate DRUJ stability with less morbidity and potentially accelerated rehabilitation compared with open repair.

Preformed spacers have proved to be effective in the two-stage revision of infected total hip replacements. In the treatment of septic arthritis of the hip, the use of a temporary device has occasionally been described, but the implantation of a preformed antibiotic-loaded spacer has not yet been reported. A 71-year-old man with a destructive Staphylococcus aureus septic arthritis of the hip joint was admitted to hospital. Given the persistence of local infection regardless of all antibiotics and the worsening of joint damage, an aggressive surgical treatment including early placement of a preformed temporary spacer loaded with antibiotics was performed. Two months later an uncemented total hip replacement was successfully implanted. Two years after surgery the patient had a complete functional recovery with no signs of recurrence. The advantages of a preformed device include an effective and predictable local release of antibiotics and a mechanically tested resistance that allows early partial weight bearing and immediate joint mobilization.

Twelve normotensive patients with coronary artery disease and stable effort-induced angina pectoris were selected: the antiischemic effect of captopril was studied. A maximal cycloergometer effort test was obtained before (base) and after administration of placebo or captopril (50 mg p.o.). The following parameters were measured: heart rate (HR), blood pressure (BP), maximal rate/pressure product (MRPP), maximal workload sustained, (MWS), maximal working time (MWT), and S-T depression at MRPP. The base and placebo were similar. Compared to them captopril augmented the MWT, increased the MWS, reduced S-T depression at MRPP, and decreased the number of patients with effort-induced angina pectoris. The antiischemic effect of captopril seems related both to its effect on HR and BP, and to a local enhancement of coronary blood flow.

The objective of this study was to assess the pharmacokientic parameters of regular nimodipine (Bayer  ), 30 mg, given every 6 h and nimodipine AP (nimodipine in micro particles with programmed action contained in tablets, developed by Biocontrolled-Leti Group Laboratories), 120 mg, given every 24 h. Subjects (19 healthy volunteers, five female; 14 male: age: 21 ± 0.7 years) received one formulation over 5 days. Then, after a washout period of 7 days, the other formulation was given. The analyst was blinded to the relationship in formulation received. Antecubital blood samples were taken before the first tablet was taken and after 15, 45, 60 min and 2, 4, 6, 8, 12, 13, 18 and 24 h on day 1 and five of each formulation. Nimodipine blood levels were analysed by HPLC. At steady-state regular nimodipine reached a C-max of 10.208 ± 0.317 ng/ml, at a t-max of 1 h; minimum concentration 6 h after dosage was 1.2929

This article presents the first steps in the investigation of the potential for digital storytelling and digital museums to be used as instruments for access, as enablers of epistemic and poietic agency. Digital storytelling and migration museums are used as a case study to explore in what ways digital storytelling impacts meaning-making processes performed by migrants, allowing them to become active creators and disseminators of their own experiences. Through the combination of corpus linguistics, systemic functional linguistics, and lexical semantic analysis, an ad-hoc comparable corpus of migrant narratives in English and in Italian was cross-examined in order to scrutinise the conceptual categories activated in these stories. The mixed-methods analysis led to the identification of the most common lexico-semantic features forming the knowledge frames of the experiential world of migrants. Results show that each national narrative makes use of its own grammar and lexico-semantic domains, a set of semantic and syntactic patterns associated with the production of stories of migration within the context of transmedia textual subtypes. These domains are strategic, as they give access to marginalised stories within digital museum settings. Lay summary Adopting the perspective of accessibility studies, digital storytelling is interpreted as a series of instruments for access, as an enabler of epistemic and poietic agency. That is, digital storytelling empowers people to express their voice and become active creators and disseminators of their own experiences. In order to investigate the potential of digital storytelling as a tool for access, we created a comparable corpus made of migrant narratives in English and in Italian spread across museum platforms. Then we  cross-examined the corpus through a combination of quantitative and qualitative methodologies in order to examine the conceptual categories activated in these stories. More specifically, we analysed and identified which linguistic strategies have been employed by the storytellers to inform the audience, what knowledge frames have been adopted to tell their experiences and expectations, and what similarities or differences exist among stories told by migrants who have settled down in different parts of the world. Showing that each national narrative makes use of its own semantic and syntactic patterns, our results support the idea of digital storytelling as an access enabler and digital museums as novel environments which jointly empower people with the tools and conditions to take a proactive role.