Folic acid (FA) supplementation is important during pregnancy to avoid malformations in the offspring. However, it is unknown if it can affect the offspring throughout their lives. To evaluate the offspring, female mother rats (Dam’s) were separated into 5 groups: Four groups received the AIN-93 diet, divided into control and FA (5, 10 and 50 mg/kg), and an additional group received a FA deficient diet, the diet was performed during pregnancy and lactation. We evaluated the female offspring of these Dam’s (at 2-and 18-months-old). The aged offspring fed with FA deficient diet presented habituation, spatial and aversive memory impairment and the FA maternal supplementation prevented this. The natural aging caused an increase in the TNF-α and IL-1β levels in the hippocampus from 18-months-old offspring. FA maternal supplementation was able to prevent the increase of these cytokines. IL-4 levels decreased in the prefrontal cortex from aged control rats and FA prevented it. FA deficiency decreased the levels of IL-4 in the hippocampus of the young offspring. In addition, natural aging and FA deficiency decreased BDNF levels in the hippocampus and NGF levels in the prefrontal cortex and FA supplementation prevent it. Thus, the present study shows for the first time the effect of FA maternal supplementation on memory, cytokines and neurotrophins in the aged offspring.
Anxiety is described as a mental and psychic response of the human body to situations of fear or threat, being manifested through various symptoms such as tremors, shortness of breath, increased heartbeat, sweating, gastrointestinal changes, among others. The Anxiety Disorder directly affects the psychological state of the individual, and may intensify his emotions and, consequently, interfere with his eating behavior. Psychological changes such as anxiety and stress can induce the individual to behave in a restrictive, compulsive, compensatory, and/or purgative way. This behavior can cause excessive consumption of food, and this consequently influences the individual's nutritional status. The aim of this study was to investigate the relationship between anxiety and eating behavior in adults through a literature review. This is a narrative literature review based on articles and theses selected from sites such as Scielo, Google Scholar, CAPES and databases of the Federal Government of Brazil, as the Health Surveillance Agency (ANVISA) and the Ministry of Health. A total of 24 articles were selected, 7 about eating behavior, 7 about nutritional status, 7 about the prevalence of anxiety and binge eating, and 3 about foods that reduce anxiety symptoms. It was possible to observe that anxiety influences the individual's eating behavior. High levels of anxiety were observed in patients with binge eating disorder, which affects the individual's nutritional status. Among genders, females have higher levels of anxiety and binge eating. The population needs interventions that reduce anxiety levels. Food plays a role in the prevention and treatment of some diseases; the effects of a healthy eating pattern bring physical and mental benefits to the individual. The Nutritionist, through food can influence the reduction of anxiety symptoms, with foods that have a beneficial influence on the body and the performance of a multidisciplinary team is essential, in order to bring more effective results.
O consumo de esteroide anabolizante vem se tornando cada vez mais comum, isso na grande maioria por padrão estético, com objetivo de ganhar músculo e melhorar a performance de forma muito mais acelerada. Porém seu uso sem a correta indicação está associado a diversos riscos à saúde. O objetivo dessa pesquisa foi avaliar a utilização de esteroides anabolizantes entre acadêmicos do curso de nutrição de uma universidade sul catarinense. Trata-se de uma pesquisa de campo, quantitativa e transversal, realizada através de questionário digital. Foi observado que a utilização de esteroides e relativamente alta entre a população avaliada 10,53%, sendo mais frequente entre os homens 75% do que entre as mulheres 25%. A metade dos usuários não tinha recomendação nem acompanhamento médico, portanto adquiriam os esteroides de forma ilegal. Observa-se na população avaliada a necessidade de uma orientação voltada a procura por indicação médica no caso do uso de esteroides anabolizantes, visando assim a redução da utilização indevida, e redução do surgimento de efeitos deletérios a saúde a médio e longo prazo.
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