The article presents the results of field experiments carried out in 2018-2020 on the fields of EkoNivaAgro LLC at the Levoberezhnoye farm (Liskinsky district, Voronezh region). The objects of the study were the Canadian soybean variety OAK Prudence, the Argentinean inoculant of the liquid formulation Nitragin Zh, the fungicidal dressing agent Delit Pro, KS, pyraclostrobin 200 g / l (BASF, Germany). Soybeans were grown using the NO-TILL technology after the predecessor corn for grain. The yield of soybean grain in the control variant (without the use of agrochemicals) was the highest in 2018, favorable for moisture (1.50 t / ha) and practically the same in 2019 and 2020. - 1.24 and 1.23 t / ha, respectively. On average for 2018–2020 the yield of soybean grain in the control variant was 1.32 t / ha. The maximum grain yield was obtained on the variant with the combined use of the inoculant Nitragin Zh and ammonium nitrate at a dose of 200 kg / ha - 2.08 t / ha. The increase in comparison with the control variant reached 0.76 t / ha, or 57.0%. The greatest influence on the technological parameters of soybean seeds was exerted by pre-sowing inoculation of seeds and pre-sowing application of nitrogen fertilizers at a dose of N70. Inoculation provided an increase in the protein content in soybean seeds by 4.1%, and the introduction of N70 by 4.3% in absolute terms compared to the control.