Purpose: Present 1-year data of the combined ophthalmology and rheumatology pediatric uveitis clinic at Leeds Teaching Hospitals.Methods: Retrospective data collectionResults: An estimated 230 patients with JIA were screened by ophthalmology in this time period.21 different paediatric patients with iritis were managed from June 2011 to May 2012 in the joint clinic.8(38%) patients were male and 13(62%) female with age at diagnosis ranged from 0.5 – 12 years. 11 patients (52%) were diagnosed with oligoarticular and 5(23%) with polyarticular JIA,3 patients were ANA +, 3(14%) did not have any joint involvement.9 patients(43%) presented with vision of 0.2logMar or worse, and 4 continued to have vision worse than 0.2 logMar while 17 patients (81%) improved or maintained stable vision of 0.1 or better.3 patients had intermediate uveitis,1 had panuveitis and 1 had papillitis with iritis.2 had eye complications of lens opacities and 1 patient had retinal detachment.17(81%) patients received systemic treatment, with 12 receiving methotrexate +/- mycophenolate mofetil and 5(29%) receiving anti-TNF α therapy (infliximab or adalimumab) in addition to methotrexate +/- mycophenolate mofetil. 13/16 patients with JIA (81%) had iritis associated with their joint flare-ups. 9 patients (50%) out of 18 with joint pathology received intra-articular steroid injections during this period and 6 received (28%) periocular steroid injection. A survey of the joint clinic by the patient and medical staff showed significantly high satisfaction rate.Conclusion: The joint clinic has numerous benefits and is the right approach to manage a condition where communication is crucial between team monitoring (ophthalmology) and managing (rheumatology) the conditio
Background
50–100 babies are born per year to drug using mothers in Leeds. Local guidelines state maternal or neonatal urine toxicology (UT) should be sent if the mother is known to use illicit substances (with the mother’s verbal consent).
A local audit was conducted alongside a national survey of the use of UT in drug exposed newborn infants.
Methodology
Survey: Representatives from all UK neonatal networks were asked about their use and local indications for UT.
Audit
The case notes of infants born to drug using women in 2012 were reviewed. UT results for infants during this period were obtained from biochemistry.
Results
Survey
32 health professionals responded in total representing 19 of the 24 UK networks. 22% sent maternal UT and 28% sent UT from the baby.
Audit
49 cases were reviewed. Maternal toxicology results were documented in 2 cases. 30 infant urine samples were received by the laboratory. 25 cases had documentation of urine being sent. 19 had documented consent. UT results identified more concerning drug use than that reported in 5/19 cases. 31 cases had discharge planning documented and urine results documented in 13/31 cases.
Discussion/Conclusions
National practice is variable with the majority of units discontinuing testing. Locally, despite sending UT, documentation is poor and testing does not alter management.
There is a need for accurate, quick and reliable testing for infants, where drug exposure is known or suspected. The use of bedside meconium testing is being piloted locally and may provide an alternative to UT.
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