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The knowledge of temperature distribution inside the tissue to be treated is essential for patient safety, workflow and clinical outcomes of thermal therapies. Microwave imaging represents a promising approach for non-invasive tissue temperature monitoring during hyperthermia treatment. In the present paper, a methodology for quantitative non-invasive tissue temperature estimation based on ultra-wideband (UWB) radar imaging in the microwave frequency range is described. The capabilities of the proposed method are demonstrated by experiments with liquid phantoms and three-dimensional (3D) Delay-and-Sum beamforming algorithms. The results of our investigation show that the methodology can be applied for detection and estimation of the temperature induced dielectric properties change.

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Temperature monitoring during thermal therapies is used to regulate the amount of heat distributed to the cancerous tissue and therefore improve the clinical outcome of the oncological treatment. For the development of a hybrid hyperthermia system with non-invasive temperature monitoring by means of ultra-wideband (UWB) imaging, the optimal configuration of sensing antennas and heating applicators has to be investigated. In this paper we present the results of numerical simulations of several possible antenna arrangements, which are then validated by experiments with the radar system. The performance of each channel configuration was analyzed and benefits for the different clinical scenarios were specified.