This is a rare presentation of a unilateral optic nerve infarction of the left eye caused by mucormycosis in a 51-year-old man with poorly controlled Type 2 diabetes. Diffusion-weighted MRI of the orbit demonstrated extensive infarction of the left optic nerve with ipsilateral cavernous sinus thrombosis and periorbital adnexal inflammation. Left orbital exenteration and sinus debridement were performed, and mucormycosis involving the optic nerve sheath was confirmed on histopathology.
Purpose: To analyze and quantify the characteristics and parameters of the eyelid and adnexa of males and females and correlate these findings to an aesthetically pleasing score. Methods: This is an Institutional Review Board approved study involving healthy male and female volunteers. The margin-to-reflex distance, palpebral fissure, inferior scleral show, tarsal platform show, and brow fat span were measured using Image J digital photographic analysis and the images were scored by 110 non-ophthalmologists. The eyelid parameters were compared between the groups with Student t tests and the total aesthetic score was correlated to the measured parameters with Pearson’s correlation coefficients (r). This study was HIPAA-compliant with protection of individually identifiable information. Results: Twenty male and 22 female participants were included and divided into 2 groups based on the aesthetic score. The average aesthetic score was 3.06 for males and 3.36 for females. None of the eyelid parameters were found to be significantly significant between the 2 male groups. In females, both inferior scleral show and tarsal platform show were significantly lower in the more aesthetic group. A greater margin-to-reflex distance correlated with increased aesthetic appeal. The ratio of brow fat span/tarsal platform show was not significantly different between the 2 female groups. Conclusions: Quantifying goals are important for the surgical and nonsurgical management of the eyelid and periorbita. Beauty is considered to be subjective and is comprised of various criteria. However, this study reveals that the female sex may have certain quantifiable goals for eyelid parameters that are considered more aesthetically pleasing.
Pediatric uveitis is uncommon, accounting for only 5% to 10% of all uveitis cases. 1 Similar to adults, children with uveitis may be asymptomatic or may present with eye pain, redness, photophobia, and blurry vision. 2 Uveitis can be categorized as anterior uveitis, intermediate uveitis, posterior uveitis, or panuveitis, depending on the part of the eye that is involved. 2,3 Diagnosis is made by examination; findings include anterior chamber (AC) cell and flare, AC fibrin, keratic precipitates, posterior iris synechiae, vitreous cell and haze, vitreous exudates (snowballs), chorioretinitis, and/or retinal vasculitis. 2 AC cell and flare can be graded based on the Standardization of Uveitis Nomenclature Criteria. 2 Complications of uveitis are extensive, including cataracts, glaucoma, hypotony, macular edema, epiretinal membrane, optic disc edema, band keratopathy, posterior synechiae, vision loss, and even permanent blindness. 2,4 Juvenile idiopathic arthritis (JIA) is the most common cause of secondary uveitis in children, with a reported incidence of 4.9 to 6.9 per 100,000 persons per year. 1,5 It is associated with chronic anterior uveitis in 10% to 30% of JIA patients. 2,4 While the majority of patients with JIAassociated uveitis maintain a good best-corrected visual acuity of 20/40 or better, 1 systematic review found that 9.4% of patients with JIA-associated uveitis had a best-corrected visual acuity worse than 20/40. 6 In addition, the incidence of cataracts was 20.5%, glaucoma was 18.9%, and band
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