Introduction ne of the most frequent nondermatologic malignancies is prostate cancer (1). Different therapeutic methods, such as new treatment options, early diagnosis, and routine screening, have positive and important effects on the survival rate of prostate cancer patients (2). Based on the statistics, in 2012, about one million men were diagnosed with prostate cancer worldwide, 70% of whom were in developed countries. The incidence of prostate cancer in Iran is about 10 per 100,000 individuals (3). It is estimated that about 43% of male cancer survivors in the United States are survivors of prostate cancer, and the rate of 5-year survival across different stages is 99.7% (4). When sound travels through a medium, it can cause turbulence in it. Sound is defined as the compression of a waveform at a specific frequency that passes through air or materials (5). A number of studies have divided sound into three groups: 1) infrasound (below 20 Hz); 2) audible sound (20-20,000 Hz), and 3) ultrasound (above 20 kHz) (6). In the field of medicine, the use of ultrasound is well-known in the diagnosis and treatment of medical problems. Sound can also create mechanical stress and directly affect cells. The disturbance created by sound via the mechanism of particle interaction is probably the cause of such an effect (7).