Studies regarding the prevalence of CLABSIs in Pakistan are limited. However, it is known that healthcare-associated infections are a concern in many low- and middle-income countries, including Pakistan. The present study is aimed to identify the relative risk of developing CLABSIs in the hospital care setups of Pakistan. The risk of biases in included studies was assessed using Cochrane tool parameters. Analysis of results revealed a relative risk of getting CLABSIs is 1.78 (p<0.001) among patients admitted in the hospitals for greater than 72 hours. This shows that the chances of getting infected at the central line site were more than 50% among patients admitted to ICUs in Pakistan. It has been concluded that the relative risk of CLABSIs in the integrated healthcare system of Pakistan is high.

Background: Nurses are an essential part of the healthcare team and require sound knowledge, safety, and protection from occupational health hazards they encounter at work. Therefore, this study aimed to assess the nurse's knowledge regarding occupational hazards, their pre-disposing, and preventive factors.   Methodology: A descriptive cross-sectional study was conducted among nurses working in surgical, general, ENT, ICU, and gyne ward of the Ziauddin and Civil hospital located in Karachi, Pakistan. A total of 157 registered nurses with a minimum of 6 months of work experience with a valid PNC license were included in the study. Systematic random sampling was used to select participants for the research. The knowledge regarding occupational hazards, pre-disposing factors, and preventive measures were recorded using a structured questionnaire.  Results: Among 157 participants, the highest occurring occupational hazard was neck and back pain, 52.9%. The assessment of pre-disposing factors to occupational hazards revealed that 70.1% of nurses distinguished lack of adequate protective aids and equipment as one of the most common reasons for the occupational hazards. However, it is revealed by 77.7% of participants that proper training and retraining on safety measures, provision of protective aids and equipment could be possible ways of preventing occupational hazards. Conclusion: It is concluded that occupational health hazards are prevalent among nursing professionals, which can be reduced through owing responsibility, gaining appropriate knowledge and skills, warrant precautionary actions for avoidance to ensure their own and others' health and well-being.