Background: Aqueous leaf extract of Moringa oleifera (MO) was evaluated for its ability to ameliorateacetaminophen-induced toxicity in albino rats using serum urea and creatinine levels as well as heamatological parameters as indices of evaluation. Methods: Groups of five Albino rats were pre-administered with MO (200 and 400mg/kg/bw) prior to a single dose administration of acetaminophen (3g/kg body weight). Haematological and biochemical indices were determined using standard methods. Results: Pretreatment of 200mg and 400 mg/kg body weight prior to acetaminophen administration caused significant reductions(p<0.05) in the test groups when compared to normal control groups in the levels of urea and creatinine in serum. There were no significant difference in the haematological parameters between the test and control groups. Conclusion: Results suggest that aqueous extract of Moringa oleifera administration would affect biologicalresponse to acetaminophen in kidney functions.

Cancer is a major leading cause of death in the world today. Breast cancer is the most common cancer in women in 140 countries. The widespread use of medicinal plants is not limited to the developing countries, there’s a renewed interest by the public and scientific organisations concerning plants and cure for diseases. The increasing cost of modern health care has made the role of ethnomedicine a very important one. A majority of the Nigerian population use traditional medicine for relief from various ailments largely due to inadequate medical facilities, high poverty rate and many other socio‐ economic/ socio‐ cultural factors. Local herbalists claim the possession of remedies useful in curing different cancer types. However, such knowledge is secretive and kept within close family circle. This work is aimed at providing an inventory of North East Nigerian plants with anti‐ breast cancer potentials for future verification and scientific validation. Semi‐structured questionnaire and oral interview were used to obtain relevant ethnomedicinal data. Twenty five different plant species were identified to possess possible anti‐ breast cancer potentials. Plant names, family, part used, relevant pharmacologic activities and pictures of plants were documented.

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Hausa in Northern Nigeria as "Kuka", "Goruba", "Magarya" and "Kurna" while their respective English names are baobab, doum palm, jujube/Chinese date and Christ's thorn. People in North East Nigeria consume the fruit of these plants and believed to have nutritional and analgesic benefits. However, there is paucity of scientific data on the medicinal benefit of the edible parts of these plants especially the fruit pulps in their single form or in combination with each other. Scanty literature on the acute toxicity of the different fruit pulps in rodents showed LD50 values of greater than 5000 mg/kg. 12-14 The present study was aimed at determining the acute toxicity and anti-nociceptive activities of a methanol extracted recipe from the edible fruit pulps of A. digitata, H. thebaica, Z. mauritiana and Z. spina-christi plants. Materials and Methods Sample collection The fruit pulps of A. digitata, Z. mauritiana and Z. spina-christi were collected in dried form from Gamboru market,