Water purification by foaming in a bubble column is a major challenge for research. It leads to the development of innovative airlift column operated under depression. Sea water clarification by bubble column is well documented, but for freshwater remains insufficiently studied. Extraction of suspended clay particles in freshwater is carried out in an airlift column. The system used is under depression and operates in a closed circuit, thanks to a recirculation tank. Methyl isobutyl carbinol (MIBC) and soluble casein are used as surfactants to allow extraction. Clay used is fine and ultra-ventilated and a turbidimeter is used to measure turbidity. This study showed that the combined use of methyl isobutyl carbinol and casein in the airlift column makes it possible to completely clarify water loaded with clay particles. A turbidity of less than 1 NTU is obtained after 30 minutes of extraction.