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Sponsored by the U.S. National Science Foundation, a workshop on the boundary element method (BEM) was held on the campus of the University of Akron during September 1–3, 2010 (NSF, 2010, “Workshop on the Emerging Applications and Future Directions of the Boundary Element Method,” University of Akron, Ohio, September 1–3). This paper was prepared after this workshop by the organizers and participants based on the presentations and discussions at the workshop. The paper aims to review the major research achievements in the last decade, the current status, and the future directions of the BEM in the next decade. The review starts with a brief introduction to the BEM. Then, new developments in Green's functions, symmetric Galerkin formulations, boundary meshfree methods, and variationally based BEM formulations are reviewed. Next, fast solution methods for efficiently solving the BEM systems of equations, namely, the fast multipole method, the pre-corrected fast Fourier transformation method, and the adaptive cross approximation method are presented. Emerging applications of the BEM in solving microelectromechanical systems, composites, functionally graded materials, fracture mechanics, acoustic, elastic and electromagnetic waves, time-domain problems, and coupled methods are reviewed. Finally, future directions of the BEM as envisioned by the authors for the next five to ten years are discussed. This paper is intended for students, researchers, and engineers who are new in BEM research and wish to have an overview of the field. Technical details of the BEM and related approaches discussed in the review can be found in the Reference section with more than 400 papers cited in this review.

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Large craniofacial defects require efficient bone replacements which should not only provide good aesthetics but also possess stable structural function. The proposed work uses a novel multiresolution topology optimization method to achieve the task. Using a compliance minimization objective, patient-specific bone replacement shapes can be designed for different clinical cases that ensure revival of efficient load transfer mechanisms in the mid-face. In this work, four clinical cases are introduced and their respective patient-specific designs are obtained using the proposed method. The optimized designs are then virtually inserted into the defect to visually inspect the viability of the design . Further, once the design is verified by the reconstructive surgeon, prototypes are fabricated using a 3D printer for validation. The robustness of the designs are mechanically tested by subjecting them to a physiological loading condition which mimics the masticatory activity. The full-field strain result through 3D image correlation and the finite element analysis implies that the solution can survive the maximum mastication of 120 lb. Also, the designs have the potential to restore the buttress system and provide the structural integrity. Using the topology optimization framework in designing the bone replacement shapes would deliver surgeons new alternatives for rather complicated mid-face reconstruction.