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In the asymmetric unit of the title compound, C10H9FN4S, there are two independent mol­ecules in which the dihedral angles between the 1,2,4-triazole and benzene rings are 36.85 (10) and 7.81 (10)°. In the crystal, N—H⋯S inter­actions link pairs of independent mol­ecules into dimers. There are also π–π inter­actions between the triazole and benzene rings of inversion-related pairs of the more planar mol­ecule [centroid–centroid distance = 3.6430 (13) Å].

Despite the fact that triazole was first synthesised over a century ago, it continues to unique the interest of chemists, biologists, technologists, and other experts.  Triazoles  have been shown to have antiviral, anti-inflammatory, anti-fertility, anti-tubercular, antimicrobial, anti-cancer, and anti-corrosion properties in recent years. The goal of this review is to describe the structures, synthesis, reactions, and spectral properties of triazoles in order to highlight their potential applications in a variety of bioactive phenomena and analytical applications.

In the title compound, C11H11FN4S, the dihedral angle between the 1,2,4-triazole ring and the benzene ring is 25.04 (12)° and an intra­moleuclar C—H⋯S inter­action leads to an S(6) ring. In the crystal, inversion dimers linked by pairs of N—H⋯S hydrogen bonds generate R 2 2(8) loops.

Reactions of 3-Substituted-4-amino-5-mercapto-1,2,4-triazoles with Acetylenic Ketones and α-Bromochalcones.-Owing to the wide range of pharmacological activity shown by 1,2,4-triazole derivatives, triazolothiadiazepines (V) are synthesized via Michael addition of mercaptotriazoles (IV) to acetylenic ketones (II). Chalcones (III) can also be used for the synthesis of (V). -(KALLURAYA, B.; D'SOUZA, A.; HOLLA, B. S.; Indian J.