The current study suggests that intravenous injection of MSCs into rabbits with chemotherapy-induced ovarian damage improved ovarian function. MSCs accomplish this function by direct differentiation into specific cellular phenotypes and by secretion of VEGF, which influence the regeneration of the ovary.

No abstract

Milk is nearly a perfect natural food and is widely used by all segments of our population especially for infants and the elderly. Organochlorine pesticides (OCPs) have been used worldwide, particularly in many African countries as in Egypt for the control of pests. OCPs are characterized by their bioaccumulation in the environment, especially in the food chain, where they find their way into the human body. The objectives of this study were initially to estimate the residual concentrations of different OCPs in three kinds of fresh and raw milk from different animals (cattle, buffalo, and goat) marketed in Egypt. Additionally, human dietary intake and risk assessment of OCPs were calculated. The tested OCPs included pp-DDT and its metabolites pp-DDD and pp-DDE; hexachlorohexanes (HCHs) including α HCH and γ HCH; heptachlor and heptachlor epoxide; aldrin and endrin; chlordane, methoxychlor, and hexachloride benzene. The recorded results revealed that goat and buffalo milk samples had the highest incidence of OCPs' contamination (75% for each), while this percentage was 50% in cow's milk. The mean values of ΣOCPs were 317.83 ± 34.11, 605 ± 50.54, and 1210.57 ± 99.55 (ppb/ww) in the examined cattle, buffalo, and goat milk samples, respectively. All examined OCPs were within the maximum permissible limits (MPLs) set by World Health Organization with only 10% of goat milk samples exceeding this MRL. The estimated daily intake, noncancer, and cancer health risk assessment of the tested OCPs revealed the potential cancer risk especially among children consuming goat's milk. The public health importance of such OCPs was discussed.

Mould contamination of milk products is a matter of significance in the field of food safety due to its related food spoilage and production of mycotoxins. This study was undertaken to investigate the incidence of mould contamination in different cheese types marketed in Zagazig city, Egypt. Roumy cheese had the highest total mould count followed by cheddar and white cheese types. The prevalent mould genera were Aspergillus, Penicillium, Cladosporium and Alternaria. Further identification of Aspergillus (A) species revealed that A. niger, A. flavus, A. parasiticus and A. ochracous are the dominant Aspergilli. The public health importance of the prevalent mould genera was discussed.

Presence of residues of heavy metals and trace elements in chicken eggs represent chemical hazards from the point of view of both Food safety sector due to consumption of contaminated eggs and poultry medicine sector due to the possible harmful effects of metals on chicken embryos, embryonic deaths, in particular. The objective of this study was to estimate the residual concentrations of the toxic metals (lead, cadmium, arsenic and nickel) and trace elements (zinc and copper) in three kinds of chicken eggs. The examined chicken eggs included balady (produced from free-range house fed chickens), commercial eggs, produced from laying hens fed on commercial ration and organic eggs produced from laying hens fed on organic based ration. A total of 60 fresh egg samples were collected randomly from (20, each) during the period from June to October 2016 Sharkia Governorate, Egypt. The achieved results declared that balady chicken eggs had the highest load of all metals examined followed by commercial and finally organic eggs. The residual concentrations of all examined metals exceeded the maximum permissible limits set by Food and Agricultural Organization (FAO)/ World Health Organization (WHO), especially in the balady {Pb (0.34± 0.03); Cd (0.18 ± 0.02); As (0.14 ± 0.017); Zn (23.17 ± 0.88); Ni (1.31 ± 0.08), and Cu (11.47 ± 0.66)}, followed by commercial then organic eggs. High metal concentrations in chicken eggs represent major hazards on both human and chicken embryos that might lead to sever toxicological implications. The adverse outcomes of the examined metals on both human and chicken embryos were discussed.