AbstractsDesign 27 infants and children with CHD (10 with VSD, 8 with ASD, 9 PDA) without heart failure, before and 12 months or more after surgical or catheter intervention. Eighty normal children served as controls. Results At presentation, age = (35.6 +/-26 months),patients were significantly shorter, height SDS (HtSDS)(−1.6 +/-1.1) and had lower BMI (15.1 +/-2.5) compared to normal controls (HtSDS = 0.25 +/-0.3, BMI = (16.4 +/-1.5). One year or more after catheter or surgical treatment the HtSDS and BMI increased significantly in patients to -0.55 +/-0.9 and 15.9 +/-1.5 respectively. Circulating concentrations of IGF-I increased from 46.8 +/-29 mcg/L before to 77.3 +/-47.6 mcg/L after intervention. The HtSDS after treatment was correlated with the IGF-I concentration (r = 0.804, P<0.001). The change in the HtSDS after intervention was correlated significantly with BMI (r=0.594, p<0.001). The shunt size was correlated negatively with BMI before intervention (r = − 0.35, P<0.01) and with HtSDS (r = -0.461, p<0.05). Conclusions These data denoted that early surgical interference and good weight gain have beneficial effect on postoperative growth spurt. The accelerated linear growth after intervention appears to be mediated through activation of the GH/IGF-I system.

Introduction: The status of embedded fistula before kidney transplant is one of the problems in patients after kidney transplant and without correct management, surely it can lead to severe complications. The vascular access of arteriovenous fistula (AVF) and its possible complications can be found using the registered data in patients who had undergone successful kidney transplant. This information may be useful to prevent possible complications in future. Objectives: This study was aimed to determine the status of vascular access before kidney transplant in patients with successful transplantation in Urmia city, Iran. Patients and Methods: This study was a historical cohort conducted on 201 patients from March 2009 to March 2012 who had undergone vascular access before kidney transplant. The related information about complications and functions of fistula were extracted from available records. Results: According to results, the patients were divided into four groups regarding fistula function including 104 patients (51.7%) with functional fistula after kidney transplant, 49 patients (24.4%) with spontaneously closed fistula, 37 patients (18.4%) with closed fistula through surgery and 11 patients (5.5%) with reduced blood flow of fistula. Conclusion: Despite the low incidence of heart failure in functional vascular access after successful renal transplantation, these patients should be followed up by cardiologists to avoid complications. Generally, closing vascular accesses after successful transplantation is not necessary.