507 A Novel Method for Quantification of Left Ventricular Hypertrabeculation/Noncompaction Using Two-Dimensional Echocardiography

Abstract

AbstractsDesign 27 infants and children with CHD (10 with VSD, 8 with ASD, 9 PDA) without heart failure, before and 12 months or more after surgical or catheter intervention. Eighty normal children served as controls. Results At presentation, age = (35.6 +/-26 months),patients were significantly shorter, height SDS (HtSDS)(−1.6 +/-1.1) and had lower BMI (15.1 +/-2.5) compared to normal controls (HtSDS = 0.25 +/-0.3, BMI = (16.4 +/-1.5). One year or more after catheter or surgical treatment the HtSDS and BMI increased significantly in patients to -0.55 +/-0.9 and 15.9 +/-1.5 respectively. Circulating concentrations of IGF-I increased from 46.8 +/-29 mcg/L before to 77.3 +/-47.6 mcg/L after intervention. The HtSDS after treatment was correlated with the IGF-I concentration (r = 0.804, P<0.001). The change in the HtSDS after intervention was correlated significantly with BMI (r=0.594, p<0.001). The shunt size was correlated negatively with BMI before intervention (r = − 0.35, P<0.01) and with HtSDS (r = -0.461, p<0.05). Conclusions These data denoted that early surgical interference and good weight gain have beneficial effect on postoperative growth spurt. The accelerated linear growth after intervention appears to be mediated through activation of the GH/IGF-I system.

Noncompaction Cardiomyopathy

“…A.G. Khosroshahi с соавт. [82] предложил метод количественной оцен-ки НМЛЖ у детей при эхокардиографии.…”

Our Study is Just an Introduction, Reply to: Noncompaction in Healthy Subjects, Dilated and Hypertrophic Cardiomyopathy, and Neuromuscular Disorders Is the Same Entity

“…The interest of one of the most famous investigators in the world about left ventricular noncompaction (LVNC) in our article ( 1 , 2 ) is a great honor and very much appreciated. In that article, we proposed a new method for echocardiographic diagnosis of LVNC.…”

Isolated Left Ventricular Apical Hypoplasia: Reporting a Case With Mild Manifestations and Different Echocardiography Features

“…A 2D echocardiogram and cardiac MRI can successfully indicate different morphological features. The early diagnosis of LV abnormalities, such as LV apical hypoplasia, is particularly important due to the difference in the prognosis and management of LV apical hypoplasia from those of other diseases with symptoms similar to LV apical hypoplasia ( 7 ). Various modalities have been introduced to diagnose LV apical hypoplasia with varying diagnostic accuracy.…”