Due to distinguishing characteristics of nanoparticles (NPs) in terms of size, shape, chemical composition, transmittal and different applications, nanotechnology is considered as an interesting domain of research. Application of metallic NPs is important because of the diminution of dimensions and thus the unique thermal, optical and electronic properties. This research attempts to explore the synthesis of zinc oxide NPs. Zinc oxide NPs have been synthesized using cherry extract under different pH, temperature and concentration and then optimum conditions for the synthesis of them were determined. For further investigations, UV-Vis spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier infrared transformation spectroscopy (FTIR) were used. The solution containing zinc oxide NPs showed a major absorbance of 378 nm which confirmed the synthesis of zinc oxide NPs, and spherical morphology of NPs was observed in SEM images. Zinc oxide NP sizes were 6.5 and 20.18 nm which are obtained by UV-Vis spectra and XRD spectrum, respectively. Also, based on the FTIR spectra of the extract obtained before and after the synthesis, the existence of the reducing agents in herbal extract was confirmed. According to this study, the biological synthesis of NPs using plant extracts can be considered as a cost-effective and efficient method of biological synthesis of NPs and it could be an appropriate replacement to typical chemical methods for the synthesis of NPs.

Introduction:Coexistence of Wilson’s disease and autoimmune hepatitis has been rarely reported in English literature. In this group of patients, there exist features of both diseases and laboratory and histopathological studies may be misleading. Medical treatment for any of these entities, per se, may result in poor response. Therefore, by considering the acute hepatitis resembling Wilson’s disease and autoimmune hepatitis, simultaneous therapy with immunosuppressive and penicillamine may have a superior benefit.Case Presentation:We present the case of a 10-year-old boy with nausea, vomiting, yellowish discoloration of skin and sclera, abdominal pain and tea-color urine. Physical examination showed mild hepatomegaly and right upper quadrant tenderness. Laboratory and histochemical studies and atomic absorption test were done and the results were highly suggestive of both Wilson’s disease and autoimmune hepatitis, in him.Conclusions:This case study highlights, although rare, the coexistence of Wilson’s disease and autoimmune hepatitis and the need to maintain a high level of awareness of this problem. Therefore, it is reasonable to consider this type of hepatitis in rare patients, with dominant features of both diseases at the same time.

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