INTRODUÇÃO: O Sistema Único de Saúde (SUS) assegura o acesso aos medicamentos, mediante a garantia da execução integral da Assistência Farmacêutica. A Organização Mundial de Saúde (OMS) desenvolveu os Indicadores do Uso de Medicamentos com o intuito de descrever e avaliar aspectos que afetam a prática farmacêutica nos centros de saúde. OBJETIVO: Conhecer a(s) classes terapêuticas mais prescritas, segundo os indicadores de prescrição médica nas Unidades de Saúde da Família (UBSF) do município de Campina Grande. MÉTODOS: O estudo baseou-se nos Indicadores de Prescrição de Medicamentos propostos pela OMS. Os medicamentos foram classificados segundo a Anatomical Therapeutic Chemical Classification (ATC) e os dados analisados utilizando-se os programas EpiInfo 2000 e Excel. RESULTADOS: Foi prescrita uma média de 1,5 medicamentos por receita médica. A porcentagem de antibióticos prescritos foi de 21,1%. Os medicamentos foram prescritos pelo nome genérico em 84,2% das prescrições e apenas 1,1% eram injetáveis. Faziam parte da lista de medicamentos padronizados 91,9% dos prescritos. O grupo farmacológico mais prescrito foi o de antibióticos (21,0%), seguido dos antiparasitários (18,4%), analgésicos e antipiréticos (15,4%), medicamentos para o aparelho digestivo (9,5%) e respiratório (9,2%). CONCLUSÕES: Percebe-se a importância de conhecer as principais demandas da comunidade, a fim de que os serviços possam planejar e realizar intervenções pertinentes às necessidades da população. Os indicadores apresentaram bons índices, demonstrando possível conseqüência da Política Nacional de Medicamentos e da realização da Conferência Municipal de Medicamentos e Assistência Farmacêutica.

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Revista Brasileira de Farmacognosia 25 (2015) 208-211 w w w . s b f g n o s i a . o r g . b r / r e v i s t a a b s t r a c tThe aim of this work was to develop and validate an analytical method for the identification of the chemical marker of Schinopsis brasiliensis Engl., Anacardiaceae. It would determine the total polyphenols and flavonoid content by spectrophotometric methodology in the dried extract of plant. The chromatographic profiles of S. brasiliensis were determined using HPLC-UV. The liquid chromatography method was conducted on a Phenomenex Gemini NX C18 column (250 × 4.6 mm, 5 m). The mobile phase consisted of 0.05% orthophosphoric acid: methanol. The flow rate was 1 ml/min and effluents were monitored at 271 nm. The retention time for gallic acid was 8.5 min. The described method has the advantage of being both rapid and easy. Hence it can be applied for routine quality control analysis of herbal preparation containing S. brasiliensis.

Dental pathologies can be caused by plaque-forming bacteria and yeast, which reside in the oral cavity. The bacteria growing in dental plaque, a naturally occurring biofilm, display increased resistance to antimicrobial agents. The objective was the evaluation of a preclinical assay of medicinal plants of the semiarid region from the northeast against oral pathogenic microorganism, aiming at bioprospecting a new product. The selection of plant material for this study was based on the ethnobotanical data on the traditional use of plants from the semiarid region. The thirty extracts were subjected to the determination of antibiofilm activity against gram-positive, gram-negative bacteria and yeast. The hydroalcoholic extract which showed positive antibiofilm activity against most of the microorganisms tested in agar diffusion assay was further tested for the determination of minimum inhibitory concentration (MIC) and Bioassay with Artemia salina. Plant samples tested in this study exhibited good antibiofilm activity for the treatment of oral problems. The Schinopsis brasiliensis showed greater activity for Pseudomonas aeruginosa and Staphylococcus aureus, but toxicity against Artemia salina.

The aim of the present study was to perform an in vitro analysis of the antimicrobial and antiproliferative potential of an extract from Anadenanthera colubrina (Vell.) Brenan (angico) and chemically characterize the crude extract. Antimicrobial action was evaluated based on the minimum inhibitory concentration (MIC), minimum bactericidal/fungicidal concentration, and the inhibition of formation to oral biofilm. Cell morphology was determined through scanning electron microscopy (SEM). Six strains of tumor cells were used for the determination of antiproliferative potential. The extract demonstrated strong antifungal activity against Candida albicans ATCC 18804 (MIC = 0.031 mg/mL), with similar activity found regarding the ethyl acetate fraction. The extract and active fraction also demonstrated the capacity to inhibit the formation of Candida albicans to oral biofilm after 48 hours, with median values equal to or greater than the control group, but the difference did not achieve statistical significance (P > 0.05). SEM revealed alterations in the cell morphology of the yeast. Regarding antiproliferative activity, the extract demonstrated cytostatic potential in all strains tested. The present findings suggest strong antifungal potential for Anadenanthera colubrina (Vell.) Brenan as well as a tendency toward diminishing the growth of human tumor cells.