Given the complexity of the tendon repair process, where the neoformed scar tissue tends to prevent or hamper the tendon from performing its normal functions, ultrasound (US) and light-emitting diode (LED) devices have been applied to modulate the tendon repair process. This study aimed to compare the anti-inflammatory and healing effects of therapeutic US and LED in an experimental model of tenotomy using histomorphometry and Raman spectroscopy. Forty Wistar rats (235 ± 8.3 g) were separated into four groups: tenotomy (TC; control), tenotomy associated with ultrasound (US; 1 MHz, 0.5 W/cm(2)), tenotomy associated with LED at 625 nm (LR; 4 J/cm(2)), and tenotomy associated with LED at 945 nm (LIR; 4 J/cm(2)), in two experimental periods of 7 and 14 days. Histomorphometry showed a decrease of inflammatory cells (macrophages and polymorphonuclear leukocytes) for the group treated with US compared to the TC group (ANOVA, p < 0.0001) and the LIR group compared to the TC group (p < 0.05) at the seventh day, indicating an anti-inflammatory effect. In relation to the LR and TC groups, there was no significant difference. Raman spectroscopy revealed that the LR group presented an increased synthesis of collagen I compared to the other treatments and the TC groups on the 14th day (p < 0.01). US therapy showed an adjuvant effect with anti-inflammatory action, and the LED therapy at 625 nm showed an increase in collagen synthesis, contributing to the process of tendon healing.

Prototecose é uma infecção rara, causada por algas do gênero Prototheca, na maioria dos casos, por Prototheca wickerhamii, espécie que acomete o homem e outros animais. Em humanos, há cerca de 100 casos descritos no mundo, sendo cinco deles no Brasil 1 5 8 9 16. É considerada infecção oportunística, acometendo principalmente indivíduos com alguma forma de imunocomprometimento 11 13 14 . Acredita-se que a transmissão ocorra por inoculação traumática e contato com solo ou água contaminados 6 . São observadas principalmente três formas da doença, a cutânea, a articular e a sistêmica. A cutânea é a mais comum; as lesões ocorrem predominantemente em áreas expostas e podem ser de vários tipos: pápulas, nódulos, placas, úlceras etc 2 . Não há consenso sobre o tratamento, sendo muito utilizados os antifúngicos sistêmicos 7 . É considerada uma doença pouco diagnosticada por ser mal conhecida e deve ser diferenciada de outras doenças, principalmente, infecções fúngicas. Nesse sentido, nosso objetivo é relatar um caso de prototecose cutânea humana, o sexto caso descrito no Brasil. Hospital Universitário de Brasília (HUB) com o diagnóstico de pênfigo foliáceo, dado em outro serviço; estava, por isso, em uso crônico de prednisona (60mg/dia inicialmente e depois 40mg/dia) havia dois anos. Apresentava ele também, havia dois meses, massa violácea, firme, bem delimitada em dorso da mão e punho direitos, medindo 8cmx6cm, na qual foi realizada biópsia para exame histopatológico e cultura. Ao exame histológico, o achado foi de processo inflamatório granulomatoso e supurativo, com hifas e corpos redondos pigmentados, compatível com feohifomicose, diagnóstico este confirmado pela cultura sendo isolado o fungo Exophiala jeanselmei. RELATO DO CASO

The congenital granular cell lesion is a rare disease that affects newborns. We present a case of a patient with nodular lesions that were located on the anterior part of the maxillary alveolar. The surgical resection of the one lesion and its histological and immunohistochemical study were made.

Background: Mucocele of the appendix is a rare condition that frequently mimics a right ovarian tumor. There is no specific imaging technique that is able to deterrmine the correct diagnosis preoperatively. Case: The case of a 60-year-old woman who presented with a mucocele of the cecal appendix mimicking an ovarian cancer, in which the diagnosis was determined intraoperatively, is reported. Results: This patient's postsurgical recovery went well, without complaints or complications, and she was discharged from the hospital on the 4th postoperative day. Two months after the surgical procedure, she remains asymptomatic. Conclusions: Mucocele of the appendix is a luminal distension of the cecal appendix caused by an accumulation of mucinous material. Its clinical presentation has nonspecific symptoms. Currently available imaging techniques do not provide a definite preoperative diagnosis. Therefore, the proper diagnosis is only made during a laparotomy. Although rare, mucocele of the appendix must be considered as a differential diagnosis of right ovarian cancer. ( J GYNECOL SURG 27:167)

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