The present study aimed to assess the association of outcomes with comprehension, adherence and behavioral characteristics of tuberculosis (TB) patients using fixed-dose combination (FDC) therapy in the city of Contagem, MG, Brazil. This study used standardized questionnaires to collect data. Outcomes included cure in 77.2% (64/ 83), noncompliance with treatment in 20.4% (17/ 83), and absence of organ failure or death cases. The rate of adherence to treatment was high (71.1% - 59/ 83), while the level of comprehension of the treatment was insufficient for the majority of patients (72.3% - 60/ 83). When a greater number of medicines was used, the chance of noncompliance with treatment increased exponentially (p = 0.00 - OR 1.72). Light-skinned black patients, alcoholics and those who live with HIV/ AIDS showed a significant association with noncompliance with treatment (p=0.039 - OR 3.38, p=0.002 - OR 4.68, and p=0.001 - OR 9.68, respectively). Comprehension also presented a significant association with noncompliance with treatment (p=0.01 and OR 5.76 and CI 1.49-22.29). The probability of noncompliance with treatment in the first few months was greater than in the subsequent months. This study demonstrates that if the TB patients had a better understanding of the treatment, the outcome would have been more favorable as regards a proper cure.
COVID-19 is an infectious disease caused by the recently discovered coronavirus
SARS-Cov-2. The disease became pandemic affecting many countries globally,
including Brazil. Considering the expansion process and particularities during
the initial stages of the epidemic, we aimed to analyze the spatial and
spatiotemporal patterns of COVID-19 occurrence and to identify priority risk
areas in Minas Gerais State, Southeast Brazil. An ecological study was performed
considering all data from human cases of COVID-19 confirmed from the
epidemiological week (EW) 11 (March 08, 2020) to EW 26 (June 27, 2020). Crude
and smoothed incidence rates were used to analyze the distribution of disease
patterns based on global and local indicators of spatial association and
space-time risk assessment. Positive spatial autocorrelation and spatial
dependence were found. Our results suggest that the metropolitan region of the
State capital Belo Horizonte (MRBH) and Vale do Rio Doce mesoregions, as major
epidemic foci in the beginning of the expansion process, have had important
influence on the dispersion of SARS-CoV-2 in Minas Gerais State. Triangulo
Mineiro/Alto Paranaiba region presented the highest risk of infection. In
addition, six statistically significant spatiotemporal clusters were identified
in the State, three at high risk and three at low risk. Our findings contribute
to a greater understanding of the space-time disease dynamic and discuss
strategies for identification of priority areas for COVID-19 surveillance and
control.
Vulnerabilidades e acesso em saúde na adolescência na perspectiva dos pais Vulnerability and access in adolescent health in view of the parents Vulnerabilidad y acceso en salud de los adolescentes en la vista de los padres
Exceto onde especificado diferentemente, a matéria publicada neste periódico é licenciada sob forma de uma licença Creative Commons -Atribuição 4.
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ABSTRACT
ARTIGO ORIGINALPerfil epidemiológico da AIDS em Contagem, Minas Gerais,
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