Subject and purpose Just as every pandemic, COVID-19 could lead to emotional and psychological disturbances among caregivers, especially in the Intensive Care Unit (ICU), where significant stress related to the influx of patients, exposure to the virus and the lack of documentation on this new SARS occurred. The present study aimed at assessing the psychological impact of COVID-19 on the caregivers at the peak of the “crisis period”. Materials and methods A survey using the Hospital Anxiety and Depression Scale (HADS) and Impact of Event Scale – Revised (IES-R) was proposed to the persons working in 5 ICUs of a French teaching hospital (April 8 to April 21, 2020). Logistic regression was performed to find independent risk factors for anxiety and post-traumatic stress disorder (PTDS). A value of p <  0.05 was considered significant. Results The incidence of anxiety and depression were 48% and 16%, respectively. PTSD (post-traumatic stress disorder) symptoms were present in 27% of respondents. The independent risk factors for developing anxiety syndrome were being assigned in COVID-19 + ICU (OR = 2.081 [95% confident interval (CI), 1.035-4.184)], and not be trained in intensive care medicine, OR = 2.570 [95% CI, 1.344-4.901]. The independent risk factors for PTSD are having a history of burn-out (OR = 4.591 [95% CI, 1.464-14.397] and not being trained in ICU, (OR = 2.155 [95% CI, 1.047-4.440]). Conclusion COVID-19 could lead to strong impact on ICU workers. These findings should lead to prevention procedures (ICU training sessions) in persons at risk.

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