Osteoclastoma is one of the most common benign tumours. The distal end of tibia is less commonly involved. The most common sites involved are proximal end of tibia, lower end of femur and distal radius. Osteoclastoma rarely affects medial malleolus and posterior malleolus of tibia and recurrence after excision is rare in younger patients.

Have a major impact on public health. AIMTo assess the awareness of Pharmacovigilance among third year medical students. MATERIAL AND METHODSThis was an observational study. The study was conducted on fifth semester medical students in the Department of Pharmacology, Government Medical College, Anantapur. A questionnaire containing 15 questions with 2-5 options were given to each student and they were asked to mark one best suitable option. We analysed data of 80 students. The results were evaluated graphically using Microsoft Excel sheet. RESULTS89.93% of students were aware of all the activities involved in Pharmacovigilance; 48.48% of the students had an idea that all the health care professionals (i.e. doctors, pharmacists, nurses) are responsible for reporting adverse drug reaction 34.84% of students had wrong perception that WHO online database for reporting ADRs was Medsafe and 31.8% thought Vigibase as online database; 48.48% had the correct understanding that CDSCO is the regulatory body for monitoring ADRs in India; 66.66% students thought that all the Adverse drug reactions (Mild, moderate, severe) irrespective of their severity have to be reported; 61% of students thought that ADR reporting is a Professional obligation; 91% of the students were aware that all the measures (Stop the drug, report ADR and treat the condition) have to be taken when an ADR is suspected. Other factors included like 68% students knew drugs banned because of ADR. Majority of students wrote Thalidomide and Nimesulide as an example for a drug banned because of ADR. CONCLUSIONThe current study revealed that medical students had good awareness.

To determine the pattern of NON STEROIDAL ANTI INFLAMMATORY DRUGS prescribing for arthritic and non-arthritic conditions in orthopedic outpatient department. METHODOLOGY: 100 prescription duplicate collected and analyzed prospectively for the pattern of NSAID prescription for arthritic and non-arthritic conditions; the drug formulation, route, frequency, duration of admission and concomitant medications results. NSAID were prescribed for nontraumatic musculo skeletal 35% pain, 25% post traumatic pain, 20% osteoarthritis, 10% postoperative pain, 3% ankylosing spondylitis, 6% degenerative disease of spine, 1% neuralgia. The NSAIDs commonly prescribed were Aceclofenac 45%, Etodolac 20%, Diclofenac 24%, and Ibuprofen 11%. Fixed dose combination of NSAIDs with adjuvante was prescribed in. The adjuvants, included are paracetamol 55.6%, serratopeptidase 32.8%, chlorzoxazone 9.1%, Thiocolchichoside 2.5%. oral formulations of NSAIDs were prescribed in all patients, supplemented by Topical formulations as gel/cream in 15% of subjects. The dosing frequency was BID (65%), OD (25%), TID (2%), SOS (8%). Duration of administration ranged from 5-15 days.other classes of drugs used concomitantly were proton pump inhibitors, calcium supplements, Multivitamins, Anti microbials, Immuno suppressants, and Glucosamine. CONCLUSION: NSAIDs were prescribed empirically for various arthritic and Nonarthritic conditions, frequently as fixed dose combinations [FDC]s with various adjuvants as per the standard guide lines. However patient information was inadequate in most of the prescriptions. Proper patient Assessment deemed necessary for individualizing NSAIDs.