IntroductionHave you ever felt like reinventing the wheel? Or would you rather use the wheels you already have more effectively? We suspect the latter… This line of thought, is worth bearing in mind when developing new policies. It is better to take stock of available concepts, instruments and tools, identify new possibilities stemming from them, and develop potential synergies, than to begin from scratch and reinvent the wheel.The same metaphor can also be applied to "technology" or "knowledge" transfer, the daily work of Steinbeis 2i GmbH. An institution focused on building the capacities of regional enterprises, so that they can pass through the so-called 'valley of death' between pure research and innovation. Steinbeis 2i GmbH facilitates the transfer of technology, both hard (e.g. new products, materials), and soft (e.g. academic concepts and policy findings) from theory to practice. This includes engagement with public and private institutions, such as ministries, business development agencies, universities and especially small and medium enterprises (SMEs). Steinbeis 2i GmbH, does not so much create new innovations, but it does make it more likely for their stakeholders to develop their own innovations.A recent opportunity to engage in this form of 'knowledge transfer' was the annual European Week of Regions and Cities (EWRC) in Brussels. Specifically, the focus of this article was a session on "Revitalising Regional Economies through Smart Specialisation and Industry 4.0", organised by Regional Studies Association, which looked at the experiences of the successful implementation of the Research and Innovation Strategies for Smart Specialisation (RIS3).Two points stood out in this session, the first was that when participants were surveyed, 50% of them agreed or strongly agreed that their region had clearly adopted a RIS3 strategy. However, at the same time, when asked where there is a need for deeper learning and exchange between regions and stakeholders, the majority of respondents answered: RIS3 implementation. Considering this anomaly, this article returns to the theoretical roots of RIS3 and provides an example from practice, which could serve to build ideas and synergies for the successful implementation of RIS3, without the need for reinventing the wheel.