This literature review is devoted to the tuberous yacon (Smallanthus sonchifolius), a perennial plant of the family Asteraceae, which is widely used in traditional medicine. Yacon tubers are characterized by a sufficiently high content of inulin for industrial production. The data provided in the review show that Smallanthus sonchifolius has a proven prebiotic effect due to its high content of fructooligosaccharides as well as other chemical compounds and has great potential as a prebiotic. In addition to the prebiotic effect, yacon has a wide range of pharmacological effects, including antidiabetic, hypoglycemic, hypolipidemic, anti-inflammatory, antitumor, immunostimulatory, antioxidant, antidepressant, hepatoprotective, spermatogenic, antibacterial, antifungal, antiparasitic, analgesic. Infusions made from yacon leaves can be not only effective agents against hyperglycemia, but also a relatively rich source of polyphenolic antioxidants. Yacon has potential as a plant supplement to treat male infertility and normalize low testosterone levels, such as in LOH-syndrome. The diversity of pharmacological action of yacon is due to the content of different groups of biologically active substances described in the review. The underground organs, leaves, and flowers of yacon contain various chemical compounds, including phenolic acids, sesquiterpene lactones, fructooligosaccharides of inulin type β (2→1), tannins, flavonoids, saponins, and anthracene derivatives.

The literary review is devoted to one-year-old sunflower (Helianthus annuus L.) - an annual herbaceous plant of the genus Sunflower (Helianthus L.), widely cultivated in the USA, Argentina, Turkey, Romania, the Russian Federation, mainly with the aim of obtaining oil from seeds. Russia produces up to 20.3% of one-year-old sunflower, which is one of the country's main food and technical crops. It accounts for over 80% of the sown areas of oilseeds, which are concentrated mainly in the Altai Territory, the Volga Region, the North Caucasus and the Central Black Earth Region. The review summarizes the information of the scientific literature on the chemical composition, biological activity of biologically active substances contained in different parts of one-year sunflower (Helianthus annuus L.). The data presented in the review show a wide range of pharmacological effects of the plant Helianthus annuus L., including anti-inflammatory, analgesic, antibacterial, antiplasmodium, anti-ulcer, antihistamine, antidiarrheic, hypolipidemic, litholytic, nephrolytic, anxiolytic, antioxidant, anticancerogenic, A wide range of pharmacological activity is due to the rich chemical composition of roots, flowers, leaves of Helianthus annuus L., which are currently used mainly in folk medicine and are cheap, available raw materials, which are the waste of processing this actively cultivated agricultural crop in the Russian Federation, which provides prospects for developing quality standards of various parts of the plant Helianthus annuus L. and medicines based on them for implementation in the medical and pharmaceutical practice of our country.