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This study examined the correlation between the clinical and laboratory diagnosis of leprosy, using biopsy results from laboratories "A" and "B" and the ML Flow test. Clinical and histopathological diagnoses presented 67.6% agreement. The laboratories showed 73.7% agreement in the bacterial index and laboratory 'B' detected 25.4% more positives. The highest agreement was in the LL form and lowest, in the I form. The highest diagnostic discrepancy was for the BB form. Clinical diagnosis agreement was 41.3% for laboratory 'A' and 54% for 'B'. The ML Flow test reclassified 10.7% of the patients. The spectrum of leprosy classification is important for a clearer understanding of the disease and its proper treatment, but is not used in health services, which use the simplified WHO criteria. This could be complemented by ML Flow testing. Such simplification is unacceptable for Leprosy Reference Centers regarding patient attendance, teaching and research, for which the standardization of the Ridley-Jopling classification is recommended. Key-words:Leprosy. Bacterial index. ML-Flow. Clinical and laboratorial agreement. RESUMOEste estudo avaliou a concordância entre o diagnóstico clínico e o diagnóstico laboratorial da hanseníase, utilizando os resultados de biópsias dos laboratórios A e B e o teste ML-Flow. A concordância diagnóstica clínico-histopatológica foi de 67,6%. Os laboratórios apresentaram um índice de concordância de 73,7% em relação ao índice baciloscópico, e o laboratório B detectou 25,4% a mais de casos positivos. A maior concordância foi obtida para a forma V, e a menor para a forma I. A maior discrepância diagnóstica ocorreu para a forma DD. A concordância clínico-laboratorial foi de 41,3% para o laboratório A e 54% para o B. O teste ML-Flow reclassificou 10,7% dos pacientes. A classificação espectral é importante para o melhor entendimento da doença e para seu tratamento adequado, mas não é utilizada em centros de saúde, que adotam os critérios simplificados da OMS, que poderiam ser complementados pelo teste ML-Flow. Tal simplificação é inaceitável para os Centros de Referência em assistência, ensino e pesquisa em hanseníase, de modo que é recomendada a padronização pela classificação de Ridley-Jopling. Palavras-chaves:Hanseníase. Índice baciloscópico. ML-Flow. Concordância clínico-laboratorial.

The physico-chemical properties of layered double hydroxides (LDHs) can be tailored to a large extent by exploiting the flexibility of their chemical composition. This report describes the synthesis and the detailed quantitative characterization of the luminescence properties of novel Eu 3+ -containing LDHs intercalated by carboxylate and β-diketonate anionic ligands. To prepare the samples, Zn 2+ , Al 3+ and Eu 3+ were coprecipitated in a ligand-rich solution containing 1,3,5benzenetricarboxylate (BTC), acetylacetonate (ACAC), and thenoyltrifluoroacetonate (TTA).Powder X-ray diffraction is supportive for the intercalation of BTC and ACAC. The presence of TTA is revealed by CHN quantification and by the photoluminescence results. Detailed spectroscopic investigation of these materials demonstrates quantum efficiencies (η) of 15 to 17% emerging from the symmetry reduction engendered by the organic ligands in the vicinity of

Layered double hydroxides (LDHs) containing Eu 3+ activators were synthesized by coprecipitation of Zn 2+ , Al 3+ , and Eu 3+ in alkaline NO 3 − -rich aqueous solution. Upon calcination, these materials transform into a crystalline ZnO solid solution containing Al and Eu. For suitably low calcination temperatures, this phase can be restored to LDH by rehydration in water, a feature known as the memory effect. During rehydration of an LDH, new anionic species can be intercalated and functionalized, obtaining desired physicochemical properties. This work explores the memory effect as a route to produce luminescent LDHs intercalated with 1,3,5-benzenetricarboxylic acid (BTC), a known anionic photosensitizer for Eu 3+ . Time-dependent hydration of calcined LDHs in a BTC-rich aqueous solution resulted in the recovery of the lamellar phase and in the intercalation with BTC. The interaction of this photosensitizer with Eu 3+ in the recovered hydroxide layers gave rise to efficient energy transfer from the BTC antennae to the Eu 3+ ions, providing a useful tool to monitor the rehydration process of the calcined LDHs.