Background: The objective of the arthroscopic treatment in tibial spine avulsion fractures (TSAF) is to achieve firm reduction and strong internal fixation while still having the patient undergo a minimally invasive procedure. Material and methods: The study was performed on 12 young patients with avulsion fracture of the anterior tibial spine. All 12 patients had type 3 Modified Meyers and McKeever fractures. The injury mechanism was direct anterior to posterior trauma in full leg length hyperextension with sport trauma reported in all cases. The physical examination revealed decreased range of motion, extension deficit, and pain during walking. Radiology, MRI, and CT pathologic findings described complete fracture of the anterior tibial spine with no clear signs of callus formation at the time of examination. All patients underwent arthroscopic suture surgical treatment. The Tegner, the Lysholm, and the International Knee Documentation Committee (IKDC) scores were used to evaluate subjective outcomes at three and six months after the surgery. Radiographs were used to assess callus formation and healing status of the fracture. Results: The mean IKDC score was 33.4 ± 23.3 (p = 0.032) preoperatively and 84.2 ± 14.3 at final follow-up (p = 0.0032, CI = 95%). The mean Tegner score improved from 3.8 ± 1.1 pre-operatively to 6.7 ± 2.2 at six months follow-up (p = 0.0231, CI = 95%). The Lysholm score differed significantly at baseline compared to final follow-up (53.7 ± 17.3 vs. 87.7 ± 9.9; p = 0.0066, CI = 95%). In all cases (n = 12), the radiographs taken after six months revealed the healing of the fracture in the anatomic position without secondary displacement. No functional knee instability was detected at the end of the study. Conclusions: The study provides preliminary promising results regarding fracture healing, knee stability, and functional subjective scores. Patient selection was a major factor of success prediction for this technique.

The all-inside technique for ACL reconstruction uses the semitendinous muscle tendon as a graft, and postoperative pain is slightly reduced. Through the full tibial tunnel technique, better anatomical graft placement is obtained with promising results, yet there are only few scientific articles comparing the two techniques. The main objective is evaluation of results after ACL reconstruction by comparing the clinical results of the two surgical techniques. A prospective study was conducted that included 63 eligible patients according to pre-established criteria. The technique used was randomly indicated to each patient. Demographics and clinical examination results were collected and subsequently stored. The assessment tools used were the International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS) and the Visual Analogue Scale (VAS) with a 6-month follow-up period. The statistical analysis was performed for preoperative follow-up scores, at 3 and 6 months. All patients were operated by the same surgical team under spinal anesthesia with nerve block and tourniquet applied.In regards to IKDC and KOOS scores, the difference between the two interventions was not statistically significant (p = .579 and p = .710). Postoperative pain was slightly reduced in patients in the all-inside\ group but without any statistical significance compared to full-tibial tunnel technique(p = .259). There were no graft ruptures or late postoperative complications. Regarding IKDC, KOOS and VAS evaluating tools, there is no statistically significant difference between the two evaluated methods for ACL reconstruction, all-inside and full tibial tunnel at 3 months and 6 months after surgery.

Self organized nanostructured oxide layers were developed on threaded surfaces of medical implants made of Ti6Al4V alloy. The synthesis was done by electrochemical anodization in phosphate/fluoride based electrolyte. By anodization in an aqueous solution of 9.34 wt.% H3PO4 and 0.4 wt.% HF the threaded surfaces were covered by continuous, self ordered nanoporous oxide layers. Scanning electron microscopy (SEM) was used to evaluate the morphology of the nanostructured layers. The diameters of the nanopores depends on anodization potential, by using U = 24 V the openings had an average diameter of 40 nm, while using U = 30V the average nanopores diameter was of 63 nm. The current density was ~10 A/m2 in the steady state of potentiodynamic stage of anodization, and below 45 A/m2 in potentiostatic stage.

Standard procedures regarding osteoblast cells deposition on different subtrates to test the biocompatibility of materials are not available. Aspects related to cells morphology depending on their number on the surface area of the substrate were studied for the first time. Osteoblasts were successfully isolated from residual bone resulted from two different patients after total hip arthroplasty. Different numbers of osteoblasts in populations (3x104 cells/cm2, 6x104 cells/cm2, 1x105 cells/cm2) were deposited on tissue culture polystyrene for 7 and 10 days of incubation. Results suggested that the protocol of osteoblasts deposition should be adjusted to assure a fair distribution of cells on the entire available area of the substrate, possible if a very good dispersion in the medium is achieved prior to deposition. Some other key factors in cells appropriate development, such as substrate nature, topography and incubation time,were detected. The present investigation helps declaring specific standards with respect to the biocompatibility testing of materials using osteoblast populations. Further investigations may lead to the creation of databases and the establishment of standards regarding bicompatibility researches that involve osteoblasts populations.