Quiste epidermoide; Quiste renal
ResumenIntroducción: El quiste epidermoide renal es una condición rara, con muy pocos reportes en la literatura 1---3 . Se realiza la revisión de la literatura disponible y la descripción de un caso sobre un quiste epidermoide renal. Materiales y métodos: Se presenta el caso de una mujer en la quinta década de la vida, con dolor lumbar derecho y hematuria macroscópica intermitente. La urotomografía muestra una lesión en la pelvis renal derecha. La pielografía evidencia un defecto de llenado y la ureteropielorrenoscopia evidencia un gran cálculo en cáliz superior. Con estos hallazgos se realiza una nefrolitotomía percutánea (NLP). El reporte histopatológico confirma la presencia de un quiste epidermoide renal. Conclusiones: El quiste epidermoide renal es una condición rara, con muy pocos reportes en la literatura. Su etiología no es clara. Hasta el momento, en los pocos casos reportados, la mayoría de los quistes renales están localizados en el parénquima renal y tan solo en algunos reportes están localizados en el sistema colector. El manejo en todos los casos ha sido la nefrectomía parcial o radical.
Introduction Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare histological variant, accounting for 1 to 3% of the invasive urothelial carcinomas, and it is typically aggressive. So far, it has not been well characterized, and the literature is based on reports and case series.
Case Report A 70-year-old male patient presenting with 4 months of constitutional and urinary symptoms, with an ultrasound finding of bilateral hydronephrosis and diffuse thickening of the bladder walls. In the cystoscopy, trigone of infiltrated appearance, a biopsy wass performed, whose immunohistochemistry revealed a PUC. The abdominopelvic image showed an infiltrative lesion that compromised the muscle of the bladder and extended to the perivesical fat, without adequate plane of cleavage with the prostate and a single hypogastric adenopathy suspected of malignancy. It was classified as cT3b vs cT4aN1M0 (chest computed tomography [CT] negative for malignancy), and the patient was submitted to a radical cystoprostatectomy, extended pelvic lymphadenectomy and non-continent urinary diversion with ileal conduit. The pathology revealed a diffuse PUC with prostatic stromal involvement and 22 of 39 lymph nodes positive for malignancy. Finally, the patient presented a series of postoperative complications and died.
Conclusion Plasmacytoid urothelial carcinoma of the bladder is a rare entity, characterized by high aggressiveness, an advanced stage at the time of diagnosis, and a poor prognosis. Currently, an aggressive approach is recommended due to its high invasive potential.
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