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Functional integration changes in regional brain glucose metabolism from childhood to adulthood. Hum Brain Mapp. 2016;37:3017-3030. 4. Di X, Biswal B. Metabolic brain covariant networks as revealed by FDG-PET with reference to resting-state fMRI networks. Brain Connect. 2012;2:275-283. 5. Horwitz B, Duara R, Rapoport SI. Intercorrelations of glucosemetabolic rates between brain regions: application to healthy males in a state of reduced sensory input.

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Everyone has become painfully aware that women (and men) with a breast cancer gene(s) have an increased "potential" to develop breast cancer. These same individuals also have an increased risk for developing uterine and ovarian cancer and in men, there is an increased potential to develop prostate cancer. A friend of mine, Dr. Henry Lynch is the man who discovered the breast cancer genes. He found two such genes in families whose women had multiple breast cancers. He called these genes BRCA1 and BRCA2. BR is the abbreviation for "breast" and CA is the abbreviation for "cancer." The first one he discovered was numbered 1 and the second gene number 2. These genes are found on chromosomes 17 and 13 respectively. Because these genes increase the carriers "potential" for several different types of cancer, each of which are hormonally mediated, the primary author refers to these genes as "hormonally" mediated cancer genes.