Fourteen female dogs diagnosed with pyometra were studied at three separate times: at diagnosis (T0) and 24 h (T1) and 10-15 days (T2) after ovariohysterectomy (OH). The means of the markers, symmetric dimethylarginine (SDMA) (17.71 to 26.54 μg/dL) and the urinary gamma-glutamyl transferase to creatinine ratio (uGGT/uCr) (1.06 to 2.62 U/mg), varied, showing an increase with time. Further, the elevation of gamma-glutamyl transferase (uGGT) (56.61 to 128.12 U/L) and the urinary protein to creatinine ratio (RPC) (0.26 to 1.24) was evident at T0 and T1. A reduction in the means of RPC, uGGT, and uGGT/uCr was observed 10-15 days after OH. Despite the elevation of these markers, the concentration of creatinine (1.11 to 1.40 mg/dL), urea (40.07 to 67.16 mg/dL), and urinary specific gravity (1.027 to 1.028) only presented slight variation. In canine pyometra, complications secondary to acute renal injury may be present that may be mild and transient in most treated animals. As elevation in SDMA and RPC preceded changes in creatinine levels for the evaluation of glomerular filtration, tubular markers could assist in the early identification of renal damage in canine pyometra.

Congenital anomalies of the reproductive system of cats and dogs are rare. Among these, the unilateral agenesis of the uterine horn (unicornuate uterus) is the most frequent anomaly. Due to its rarity and few reports in literature, the aim of this work is to report the finding of uterine segment aplasia in a bitch during elective ovariohysterectomy. Traction of the right uterine horn was attempted after a retro umbilical celiotomy, disclosing a malformation characterized by shortening of the uterine horn, which measured 12 mm with the ovary close to the reduced segment. Malformation encountered during surgical procedures result in difficulties for the surgical team and prolonged surgical time, since other organs and systems can also present anomalies and require therefore careful inspection.