Aims/Introduction
Type 2 diabetes mellitus has been a leading cause of chronic kidney disease (CKD), with a heterogeneous distribution worldwide. Optimal healthcare planning requires an understanding of how the burden of CKD as a result of type 2 diabetes mellitus has changed over time and geographic location, as well as the potential roles of sociodemographic, clinical and behavioral factors in these changes.
Materials and Methods
We used the Global Burden of Disease data from 1990 to 2017 at the global, regional and national levels to investigate changes in the incidence, death and disability‐adjusted life years of CKD as a result of type 2 diabetes mellitus, incorporating both epidemiological research and risk factor monitoring.
Results
The incident cases of CKD as a result of type 2 diabetes mellitus worldwide in 2017 had increased by 74% compared with 1990; total disability‐adjusted life years had increased by 113%, mainly attributable to population expansion and demographic transition. The Sociodemographic Index was significantly and negatively correlated with overall CKD as a result of type 2 diabetes mellitus burden. However, in 82 countries and territories, the burden was not alleviated in parallel with socioeconomic development.
Conclusions
CKD as a result of type 2 diabetes mellitus has been the main contributor to the increasing burden of CKD over the past several decades. We suggest a more pragmatic approach focusing on early diagnosis, primary care and adequate follow up to reduce mortality and the long‐term burden in low‐to‐middle Sociodemographic Index regions. Interventions should address high systolic blood pressure, as well as overweight and obesity problems, especially in high‐income regions.
Producing ultra-stabilized radicals via light irradiation has raised considerable concern but remains a tremendous challenge in functional materials. Herein, optically actuating ultra-stable radicals are discovered in a sterically encumbered and large πconjugated tri(4-pyridyl)-1,3,5-triazine (TPT) ligands constructed photochromic compound Cu 3 (H-HEDP) 2 TPT 2 •2H 2 O (QDU-12; HEDP=hydroxyethylidene diphosphonate). The photogeneration of TPT• radicals is the photoactive behavior of electron transfer from HEDP motifs to TPT units. The ultra-long-lived radicals are contributed from strong interchain π-π interactions between the large π-conjugated TPT components, with the radical lifetime maintained for about 18 months under ambient conditions. Moreover, the antiferromagnetic couplings between TPT • radicals and Cu 2+ ions plummeted the demagnetization to 35% of its original state after light irradiation, showing the largest room temperature photodemagnetization in the current radicalbased photochromic materials.
Particulate matters (PMs) air pollution has become a serious environmental issue due to its great threat to human health. Herein, metal-organic complexes PBM-Zn1 and PBM-Zn2 coatings (noted as PBM-Zn-Filter) have been produced by the hot-pressing method on various substrates for the first time. Layer-by-layer PBM-Zn-Filters were also obtained through varying hot-pressing cycles. The obtained PBM-Zn-Filters with high robustness show excellent performance in PMs removal. In particular, benefiting from thelarger conjugation system, micropore structure, lower pressure drop, higher electrostatic potential ζ, and electron cloud exposed metal center of PBM-Zn2 (DFT calculations), PBM-Zn2@melamine foam-4 gives the highest removal rates, PM2.5:99.5% ± 1.2% and PM10:99.3% ± 1.1%, and the removal efficiency for capture PM2.5 and PM10 particles in cigarette smoke were both retained at high levels (>95.5%) after 24 h tests. More importantly, a homemade mask is made up by imbedding the PBM-Zn2@melamine foam-4 into a commercial breathing mask, which shows higher removal efficiency, lower pressure drop, smaller thickness, and higher quality factor than two commercial breathing masks, the PMs removal efficiencies for both PM2.5 and PM10 are 99.6% ± 0.5% and 99.4% ± 0.8%, and acceptable air resistance are demonstrated.
The photogeneration of stable radicals is important but still challenging in the field of optical switching, displays and other devices. Herein, the crystalline 9-anthracene carboxylic acid (9-AC) and a mononuclear...
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