Various dermatological manifestations have been observed in patients with Coronavirus disease (COVID-19) infection ranging from maculopapular rashes, urticaria, chickenpox-type lesions, chilblain-like, distal-limb ischemia, and livedo racemosa. While most of these cutaneous findings are self-resolving, they may aid in the timely diagnosis of this infection. We are reporting three patients presenting with dermatological features resembling (i) varicella zoster, (ii) herpes labialis, and (iii) Steven Johnson Syndrome (SJS) who were subsequently diagnosed with Covid-19 infection. The skin lesions disappeared after successful treatment of Covid-19.
<p class="abstract"><strong>Background: </strong>Although there are multiple treatment options, viral warts are known for their persistence and recurrence. Surgical autoimmunization is believed to work by inducing a cell-mediated immune response to clear verrucae-inducing human papillomavirus from the body.</p><p class="abstract"><strong>Methods:</strong> The study was conducted as a non-randomized interventional study at a Tertiary Care Hospital in North Eastern India. All patients above 18 years of age attending the Dermatology Clinic who were diagnosed as having multiple warts were included in the study. Autoinoculation was performed after taking patient’s consent and patients were followed up monthly for 3 months. Photographs were taken at each visit to have an objective comparison, and results assessed at the end of 3 months.</p><p class="abstract"><strong>Results:</strong> Out of 65 patients, 18 patients were lost to follow up and 47 patients completed the study. Complete resolution was found in 17 patients and 10 patients had partial resolution at the end of the study. The response was higher in those from the rural population compared to those from the urban areas and also in those with a short duration of the disease.</p><p class="abstract"><strong>Conclusions: </strong>Autoinoculation is an effective and safe treatment modality especially in palmoplantar warts. Early intervention is required as the response was better in patients with a short duration of the disease, which was statistically significant. Further studies should be done in other clinical variants of warts to see for significant response.</p>
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