Acro-osteolysis is an osteolysis of the distal phalanges of the hands and feet and can affect the terminal tuft or the shaft of the distal phalanx (transverse or band acro-osteolysis). It is often associated with distal digital ischemia, digital calcinosis, or severe sensory neuropathy. Acro-osteolysis has been associated with a heterogeneous group of disorders, including occupational activities, infections, rheumatic disorders (systemic sclerosis, psoriatic arthritis), endocrinopathies, genetic disorders, and lysosomal storage disorders. Plain radiography is the gold standard for the detection of acro-osteolysis.

Anatomage (Anatomage, Inc., San Jose, CA) is a modern method for studying anatomy. It is a state-of-the-art method used for the representation of the structure of the human body. In our study, we examined the seventh cranial nerve of a male Caucasian cadaver using an Anatomage Table in the Anatomy Department of the School of Medicine, National and Kapodistrian University, Athens, Greece. After exiting the skull from the stylomastoid foramen, the facial nerve divided into the temporofacial and cervicofacial main branches. The cervicofacial branch divided into its own branches, including the marginal mandibular nerve (MMN), which ran within the investing (superficial) layer of the deep cervical fascia. We found a variation of the course of the marginal mandibular branch of the facial nerve. In the area of the lower border of the mandible, where the MMN actually crossed the facial artery and vein, it appeared to run deeper than both of those vessels, rather than running superficially. This seemed to be a rare variation of the location of the MMN relative to the facial vessels, which suggested that extra care is essential in surgical approaches within this area.

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